江苏省中医院非小细胞肺癌患者的中医证治研究

发布时间：2018-07-23 12:41

【摘要】：目的：本研究的目的是确定和分析非小细胞肺癌(NSCLC)的中医辩证、治疗原则及常用中药、包括年龄、性别、职业、相关疾病、家族史、病理分期和肿瘤标志物。材料于方法：按标准纳入与排除、收集2015年5月～2015年12月于江苏省中医院住院的非小细胞肺癌病例115例。随着这项研究专门设计的形式帮助收集的数据进行分析、利用SPSS 21和Excel统计软件。结果：研究数的分析显示115例(非小细胞肺癌)中、男性64例、女性51例、平均年龄64.42±8.76岁。男女之比为1.25：1。其中79例患者无吸烟史(68.7%)、36例患者有吸烟史(31.3%)。非小细胞肺癌的发病率最高的年龄组61-70岁；共47例(40.9%)。共计六个证候、四个虚证、两个实证。夹杂证候为特征、没有单一证型。62.6%气阴两虚、25.2%脾肺两虚、5.2%气滞血瘀、2.6%肺肾气虚、2.6%痰湿壅肺、1.7%气血两虚。证候性质在不同临床分期与非小细胞肺癌不同病理亚型几乎相同。通过数据分析总结出17种不同的治法、9个治法用于治疗气阴两虚证候、而4个治法用于治疗脾肺两虚证候。115例非小细胞肺癌患者的治疗中、共用223个药物、包括草药、动物药及矿物质。其中、204种草药、14种动物药和5种矿物药。肺肾两虚与肿瘤标志物CEA、CA125、CA199对比经统计学比较有差异(P0.05)。结论：共有6个证候、气阴两虚、脾肺两虚、气滞血瘀、肺肾两虚、痰湿壅肺、气血两虚。为管理这些综合征的非小细胞肺癌患者中、共17的治疗原则是采用223味药物包括204种不同的中药材、14种不同的动物产品、和5种不同的矿物。
[Abstract]:Objective: the purpose of this study was to determine and analyze the traditional Chinese medicine (TCM) dialectical, therapeutic principles and traditional Chinese medicine for (NSCLC), including age, sex, occupation, related diseases, family history, pathological stages and tumor markers. Materials and methods: 115 cases of non-small cell lung cancer (NSCLC) hospitalized in Jiangsu Provincial Hospital of traditional Chinese Medicine from May 2015 to December 2015 were collected and excluded according to the standard. Along with the study's specially designed form to help collect data for analysis, use SPSS 21 and Excel statistical software. Results: there were 115 cases of non-small cell lung cancer (NSCLC), 64 males and 51 females with an average age of 64.42 卤8.76 years. The ratio of men to women is 1.25: 1. Among them, 79 patients had no smoking history (68.7%) and 36 patients had smoking history (31.3%). The highest incidence of non-small cell lung cancer (NSCLC) was 61-70 years old in 47 cases (40.9%). A total of six syndromes, four deficiency syndrome, two empirical evidence. There was no single syndrome type. 62.6% Qi and Yin deficiency was 25.2% spleen and lung deficiency was 5.2% Qi stagnation and blood stasis was 2.6% phlegm dampness in lung was 1.7% qi and blood deficiency. The syndromes were almost the same in different clinical stages and different pathological subtypes of non-small cell lung cancer (NSCLC). Through data analysis, 17 different treatment methods were summarized, 9 were used to treat Qi and Yin deficiency syndrome, and 4 were used to treat spleen and lung deficiency syndrome. 115 patients with non-small cell lung cancer were treated with 223 drugs, including herbal medicine. Animal medicine and minerals. There are 204 kinds of herbs, 14 kinds of animal medicine and 5 kinds of mineral medicine. There was significant difference between lung and kidney deficiency and tumor marker CEA CA125, CA199 (P0.05). Conclusion: there are 6 syndromes: deficiency of qi and yin, deficiency of spleen and lung, stagnation of qi and blood stasis, deficiency of lung and kidney, phlegm and dampness of lung, deficiency of qi and blood. In order to manage these syndromes in non-small cell lung cancer patients, a total of 17 treatment principle is to use 223 drugs, including 204 different kinds of traditional Chinese medicine, 14 different animal products, and 5 different minerals.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R273

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