论瘀血学说与冠心病

发布时间：2018-07-25 20:21

【摘要】：目的:研习古代文献关于“瘀血”的论述,系统整理总结“瘀血”学说;运用“瘀血”学说论治冠心病的机理及应用前景作初步探讨,以期为该病的中医药治疗提供新的思路和借鉴。方法:(1)运用文献检索学的方法广泛收集有关瘀血基础理论研究的资料,根据不同历史时期依序对资料进行分类汇总;(2)阐述瘀血在冠心病形成中的重要作用;(3)论述冠心病血瘀证的现代物质基础,包括生理病理、生化、细胞分子等多项实验参数改变;(4)结合导师多年的临证经验和临床案例,分析从瘀论治的临床效果,以期探讨瘀血学说的有效性及其推广应用的意义。结果:(1)瘀血是中医学中的病理产物和致病因素,是气血失调、血行涩滞,或离经之血着而不去的病理产物。(2)饮食失节、劳逸不当、内伤七情等均可致瘀血内生,导致心脉阻滞,发为胸痹心痛;(3)随着中医理论的现代化研究不断发展,对血瘀辨证的客观化研究亦不断深入,冠心病血瘀证与血液理化、分子生物学指标、代谢组学及其他病理参数密切相关,可作为冠心病血瘀辨证分型的客观依据;(5)祛瘀活血中药临床证实可从多方面有效改善冠心病患者症状及生活质量;(6)导师方显明教授运用活血化瘀法治疗冠心病的经验、医案及其他医家的治疗特色进一步体现出后世医家对瘀血理论的继承和发扬。结论:瘀血既是中医病因学中重要的致病因素,又是体内脏气失调、气血津液运行不畅的病理产物,久病伤及脏气,形成冠心病脏虚与瘀血互结的病理过程,贯穿于冠心病的发生发展中。现代医家长期的临床实践和实验研究也发现,冠心病为本虚标实之证,正虚为本病的内在基础,瘀血为本病的继发因素,标本同治之法治疗冠心病不失为一种治病求本的有效途径,值得广泛推广。
[Abstract]:Objective: to study the exposition of "blood stasis" in ancient literature, systematically summarize the theory of "blood stasis", and discuss the mechanism and application prospect of treating coronary heart disease with "blood stasis" theory. In order to provide new ideas and reference for TCM treatment of the disease. Methods: (1) the basic theory of blood stasis was widely collected by the method of literature retrieval. According to different historical periods, the data are classified and summarized; (2) the important role of blood stasis in the formation of coronary heart disease is expounded; (3) the modern material basis of blood stasis syndrome of coronary heart disease is discussed, including physiology, pathology, biochemistry, and so on. (4) combined with many years of clinical experience and clinical cases, the clinical effect of treating blood stasis was analyzed in order to explore the validity of blood stasis theory and its significance of popularization and application. Results: (1) Blood stasis is the pathological product and pathogenic factor in traditional Chinese medicine. It is the pathological product of qi and blood disorder, blood stagnation, or not going away from the blood of the meridian. (3) with the development of modern research on TCM theory, the objective study of blood stasis syndrome differentiation is also deepening. The blood stasis syndrome of coronary heart disease is closely related to blood physicochemical, molecular biological indexes, metabolomics and other pathological parameters. It can be used as the objective basis of syndrome differentiation and classification of coronary heart disease (CHD); (5) the clinical proof of removing blood stasis and activating blood circulation can effectively improve the symptoms and quality of life of patients with coronary heart disease in many ways; (6) Professor Fang Xianming's experience in treating coronary heart disease with the method of activating blood circulation and removing blood stasis. The characteristics of medical records and other physicians further reflect the inheritance and development of blood stasis theory. Conclusion: blood stasis is not only an important pathogenic factor in the etiology of traditional Chinese medicine, but also a pathological product of disorder of visceral qi and body visceral qi. Throughout the occurrence and development of coronary heart disease. The long-term clinical practice and experimental research of modern doctors also found that coronary heart disease is the syndrome of deficiency, the deficiency of positive is the internal foundation of the disease, and blood stasis is the secondary factor of the disease. The treatment of coronary heart disease with specimen therapy is an effective way to cure coronary heart disease and is worth popularizing widely.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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