新疆喀什地区西北燥证对慢性阻塞性肺疾病的影响

发布时间：2018-08-06 09:45

【摘要】：目的:通过问卷调查,明确新疆喀什地区不同民族慢阻肺患者西北燥证的罹患情况,探讨西北燥证对新疆喀什地区慢阻肺患者病情及证情的影响,以期为慢性阻塞性肺疾病的高危人群筛查,以及中西医结合临床干预提供理论依据。方法:调查研究喀什地区第一、第二人民医院明确诊断为慢阻肺的患者及喀什地区各社区门诊未患有相关疾病且民族、性别相同、年龄相当的健康居民发放西北燥证调查量表进行调查并收回,对两组数据进行病例对照研究及统计分析,发现两组数据的差异性,明确西北燥证对新疆喀什地区慢阻肺的影响作用。结果:(1)慢阻肺组汉族男性与女性西北燥证患病情况均高于对照组,且慢阻肺组汉族女性西北燥证患病率显著高于男性;在慢阻肺患者中维吾尔族男性与女性西北燥证患病情况明显高于非西北燥证患病者,且维吾尔族女性西北燥证患病率显著高于本民族男性。同时西北燥证对慢阻肺的发病存在民族差异性,慢阻肺患者中汉族罹患西北燥证的情况高于维吾尔族。(2)西北燥证对COPD的相对危险度OR值为8.11,慢阻肺组西北燥证患者西医病情积分与西医证情指数明显高于未患西北燥证者,慢阻肺病情严重程度受西北燥证的影响作用明显。(3)慢阻肺组肺卫孔窍皮肤燥证与肝肾精血不足证患病程度明显于对照组。研究发现肺卫孔窍皮肤燥证为汉族慢阻肺患者西北燥证患病的主要表现特点,而脾胃蕴湿证为维吾尔族慢阻肺患者的主要表现特点。女性西北燥证患者主要证候表现为肝肾精血不足证。(4)慢阻肺患者中西北燥证患病者虚证以气虚证表现明显,阴虚证表现次之。慢阻肺患者中维吾尔族阴虚证及气虚证的患病严重程度均高于汉族,其女性患者的阴虚证、气虚证罹患严重程度均高于男性,男性阳虚证患病严重程度高于女性。结论:慢阻肺患者中,女性受西北燥证影响的程度大于男性,汉族较维吾尔族更易罹患西北燥证;肺卫孔窍皮肤燥证为汉族西北燥证患病的主要表现特点,脾胃蕴湿证为维吾尔族患者的主要表现特点。女性患者主要证候特点为肝肾精血不足证。肺卫孔窍皮肤燥证、肝肾精血不足证与新疆喀什地区COPD稳定期中医证候关系最紧密。慢阻肺患者中,西北燥证患者虚证以气虚证多见,阴虚证次之;维吾尔族气虚及阴虚证均比汉族严重;女性患者虚证证候以气虚证和阴虚证为主要表现,男性则以阳虚证为主要证候。
[Abstract]:Objective: to investigate the attack status of northwest dryness syndrome of different nationalities in Kashi area of Xinjiang by questionnaire, and to explore the influence of northwest dryness syndrome on the condition and syndromes of chronic obstructive lung patients in Kashi area of Xinjiang. In order to provide theoretical basis for high-risk screening of chronic obstructive pulmonary disease and clinical intervention of integrated Chinese and western medicine. Methods: the first and second people's Hospital in Kashi area were investigated. The patients diagnosed as COPD and the outpatients of each community in Kashi area were not suffering from related diseases and had the same gender. The healthy residents of the same age issued the Northwest dryness Survey scale to investigate and retract it. The data of the two groups were analyzed by case-control study and statistical analysis, and the differences between the two groups of data were found. The effect of northwest dryness syndrome on chronic obstructive lung in Kashi area of Xinjiang was clarified. Results: (1) the prevalence rate of northwest dryness syndrome in Han nationality and female in COPD group was higher than that in control group, and the prevalence rate of northwest dryness syndrome was significantly higher in COPD group than in male. The prevalence of northwest dryness in Uygur and female was significantly higher than that in non-northwest dryness, and the prevalence of northwest dryness in Uygur women was significantly higher than that in male. At the same time, the Northwest dryness Syndrome has national differences in the pathogenesis of COPD. The incidence of northwest dryness syndrome was higher in Han nationality than that in Uygur nationality. (2) the OR value of northwest dryness syndrome to COPD was 8.11. The scores of western medicine disease and western medicine syndrome information index of patients with northwest dryness syndrome in chronic obstructive lung group were significantly higher than those without northwest dryness syndrome. The severity of chronic obstructive pulmonary disease was significantly affected by northwest dryness syndrome. (3) the disease degree of skin dryness syndrome of lung Wei Kong orifices and deficiency of liver and kidney essence and blood in chronic obstructive lung group was significantly higher than that in control group. It was found that the skin dryness syndrome of lung Wei Kong orifices was the main characteristic of northwest dryness syndrome in Han patients with chronic obstructive lung disease, while the spleen and stomach dampness syndrome was the main characteristic of Uygur patients with chronic obstructive lung disease. The main syndromes of female northwest dryness syndrome were deficiency of liver and kidney essence and blood. (4) deficiency of qi syndrome was the main syndrome of northwest dryness syndrome in chronic obstructive lung patients, followed by yin deficiency syndrome. The severity of Yin-deficiency syndrome and Qi-deficiency syndrome in Uygur is higher than that in Han nationality, and the severity of Yin-deficiency syndrome and Qi-deficiency syndrome in female patients are higher than that in male, and the severity of male yang deficiency syndrome is higher than that of female. Conclusion: in the patients with COPD, women are more affected by northwest dryness syndrome than men, the Han nationality is more likely to suffer from northwest dryness syndrome than the Uygur nationality, and the skin dryness syndrome of lung Wei Kong orifices is the main characteristic of northwest dryness syndrome in Han nationality. Spleen and stomach dampness syndrome is the main characteristic of Uygur patients. The main syndromes of female patients are deficiency of liver and kidney essence and blood. The syndrome of skin dryness of lung Wei Kong orifices and deficiency of liver and kidney essence and blood are most closely related to the TCM syndromes of stable period of COPD in Kashi region of Xinjiang. Among the patients with chronic obstructive pulmonary disease, deficiency syndrome of qi was more common in northwest dryness syndrome, followed by yin deficiency syndrome; qi deficiency and yin deficiency syndrome were more serious in Uygur nationality than in Han nationality; deficiency syndrome of female patients was mainly manifested by qi deficiency syndrome and yin deficiency syndrome. Male with yang deficiency as the main syndromes.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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