高胆固醇血症患者的bapwv结果分析其中医体质分布

发布时间：2018-08-14 12:08

【摘要】：目的:探讨高胆固醇血症与肱踝脉搏波传导速度(bapwv)的相关性,初步探讨高胆固醇血症与中医体质的相关性,及bapwv与中医体质的相关性,为动脉硬化的早期发现和心血管疾病的危险分层提供中西医理论依据,指导临床治疗。材料与方法:选取2016年6月-2016年12月于我院心内科门诊体检者84例为研究对象,其中高胆固醇血症者为观察组共43例,其中男17例,女26例,平均年龄61.26±10.14岁;血脂正常者为对照组共41例,其中男16例,女25例,平均年龄57.88±11.90岁。西医诊断标准参照《2016年ESC/EAS血脂异常管理指南》制定,中医体质分型及标准参照《中医体质分类判定表》结合舌、脉进行评估,bapwv的检测采用日本VS-1000动脉硬化诊断仪进行检测。入组患者进行基本资料录入和病史情况采集,并填写中医体质分类判定表。所有数据采用SPSS17.0统计软件分析,P0.05说明差异具有显著性。结果:1.bapwv与总胆固醇水平成正相关。2.高胆固醇血症组体质以血瘀质居多,其次分别为痰湿质和平和质;对照组体质以平和质居多,其次分别为阳虚质和湿热质。3.痰湿质、血瘀质为高胆固醇血症的危险体质。4.高胆固醇血症组体质间bapwv值的比较:气虚质血瘀质湿热质阳虚质痰湿质阴虚质平和质气郁质。结论:高胆固醇血症与肱踝脉搏波传导速度存在正相关关系,通过分析高胆固醇血症患者的bapwv结果综合评估其动脉硬化程度,为动脉硬化的早期发现和评估心血管疾病风险提供理论依据。通过对个体中医体质的评定,及时干预高危体质,“治未病”未病先防,对降低疾病的发病率有着重要意义。
[Abstract]:Objective: to investigate the correlation between hypercholesterolemia and brachial pulse wave velocity (bapwv), the relationship between hypercholesterolemia and TCM constitution, and the correlation between bapwv and TCM constitution. To provide theoretical basis for early detection of arteriosclerosis and risk stratification of cardiovascular disease, guiding clinical treatment. Materials and methods: from June 2016 to December 2016, 84 patients with hypercholesterolemia were selected as the study subjects, including 17 males and 26 females, with an average age of 61.26 卤10.14 years. There were 41 normal blood lipids in the control group, including 16 males and 25 females, with an average age of 57.88 卤11.90 years. The diagnostic criteria of western medicine were formulated according to the guidelines for the management of ESC/EAS dyslipidemia in 2016. The constitution classification of TCM and the criteria of TCM constitution classification were combined with tongue and pulse to evaluate the blood vessel. The VS-1000 arteriosclerosis diagnostic instrument of Japan was used to test the diagnostic criteria. The basic data and medical history were collected, and the TCM constitution classification form was filled out. All the data were analyzed by SPSS17.0 statistical software (P0.05). Results: 1. Bapwv was positively correlated with total cholesterol level. In hypercholesterolemia group, blood stasis was the most, followed by phlegm dampness, peace and quality, in control group, Yang deficiency and damp-heat were followed. 3. Phlegm dampness and blood stasis are dangerous constitution of hypercholesterolemia. Comparison of bapwv values between the hypercholesterolemia group: Qi deficiency blood stasis dampness heat Yang deficiency phlegm wet yin deficiency and qi stagnation. Conclusion: there is a positive correlation between hypercholesterolemia and brachial pulse wave velocity. The degree of arteriosclerosis was evaluated by analyzing the bapwv results of hypercholesterolemia patients. To provide theoretical basis for early detection and assessment of cardiovascular disease risk of atherosclerosis. It is of great significance to reduce the incidence of disease by evaluating the physique of individual TCM, intervening in high risk constitution in time and preventing the disease before treatment.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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