“眠十针”治疗原发性失眠症的临床研究

发布时间：2018-08-15 16:35

【摘要】：目的观察“眠十针”对原发性失眠症患者的睡眠时间、质量的改善及脑血流的影响,评价其临床疗效,并初步探讨其作用机理,为治疗原发性失眠症探索一个施治方便、操作规范、标本兼治、高效安全的临床治疗方法。方法从2014年5月-2016年2月中国人民解放军第255医院中医科门诊患者中选择符合纳入标准的原发性失眠症患者70例,按就诊顺序分为“眠十针”治疗组、口服艾司唑仑片对照组各35例,治疗组针刺百会、神庭、神门(双)、三阴交(双)、太溪(双)、太冲(双),每日治疗1次,10次为一个疗程,连续治疗3个疗程,对照组每日睡前口服1次,每次1-2mg,连续服药30天,治疗结束后,观察评价治疗前后二组临床疗效、匹兹堡睡眠质量指数、中医症状积分及TCD的变化,1个月后评价复发情况。结果治疗前两组病人在性别、年龄、病程方面进行比较,差异无统计学意义(P0.05),具有可比性。治疗组与对照组治疗后在中医症状积分,匹兹堡睡眠质量指数,入睡时间,睡眠质量,睡眠时间,睡眠效率,日间功能方面评分均有明显改善,差异有统计学意义(P0.01)。两组治疗后左侧椎动脉、右侧椎动脉、基底动脉TCD各指标均有改善,差异有统计学意义(P0.05)。“眠十针”治疗组临床治愈10例,显效14例,有效8例,无效3例,总有效率为91.42%,艾司唑仑片对照组临床治愈5例,显效10例,有效12例,无效8例,总有效率为77.14%,两组临床疗效比较,差异有统计学意义(P0.05),治疗组疗效优于对照组。结论1“眠十针”治疗原发性失眠症能够提高患者的睡眠质量和睡眠效率,缩短入睡时间,减少噩梦次数,使日间功能恢复正常。2“眠十针”治疗原发性失眠症疗效优于口服西药艾司唑仑片。3“眠十针”能够改善原发性失眠症患者椎-基底动脉供血不足情况,增加脑血流量,从而有利于改善脑功能。4“眠十针”疗效确切,施治方便,无副作用,适宜临床推广应用。
[Abstract]:Objective to observe the effects of "Sleeping Ten Needles" on sleep time, quality improvement and cerebral blood flow in patients with primary insomnia, to evaluate its clinical efficacy, and to explore its mechanism, so as to explore a convenient treatment for primary insomnia. Standard operation, both symptoms and symptoms, effective and safe clinical treatment. Methods from May 2014 to February 2016, 70 patients with primary insomnia, who met the inclusion criteria, were selected from the outpatient clinic of TCM Department, 255 Hospital of the Chinese people's Liberation Army, and were divided into "Sleeping Ten Needle" treatment group according to the order of visit. The treatment group was treated with acupuncture, Shenting, Shenmen (double), Sanyinjiao (double), Taixi (double), Taichong (double), and treated once a day for 10 times as a course of treatment and 3 consecutive courses of treatment. The control group took orally once a day before bedtime, 1-2mgeach time for 30 days. After the treatment, the clinical effect, Pittsburgh sleep quality index, TCM symptom score and TCD were observed and evaluated before and after treatment, and the recurrence was evaluated after one month. Results there was no significant difference in sex, age and course of disease between the two groups before treatment (P0.05). The scores of TCM symptom score, Pittsburgh sleep quality index, sleep time, sleep quality, sleep time, sleep efficiency and daytime function were significantly improved in treatment group and control group (P0.01). After treatment, TCD of left vertebral artery, right vertebral artery and basilar artery were improved in two groups, the difference was statistically significant (P0.05). In the treatment group, 10 cases were cured, 14 cases were effective, 8 cases were effective, 3 cases were ineffective. The total effective rate was 91.42%. In the control group, 5 cases were cured, 10 cases were effective, 12 cases were effective, and 8 cases were ineffective. The total effective rate was 77.14. The difference between the two groups was statistically significant (P0.05). The curative effect of the treatment group was better than that of the control group. Conclusion 1Sleeping ten needles in the treatment of primary insomnia can improve the sleep quality and sleep efficiency, shorten the time to sleep and reduce the number of nightmares. The curative effect of "Sleeping Ten Needles" on the treatment of primary insomnia was better than that of "Sleeping Ten Needles" in the treatment of primary insomnia with oral eszolam tablet .3 "Sleeping Ten Needles", which could improve the blood supply of vertebrobasilar artery and increase cerebral blood flow in patients with primary insomnia. Therefore, it is beneficial to improve brain function. 4. "Sleeping Ten Needles" is effective, convenient and no side effect. It is suitable for clinical application.
【学位授予单位】：华北理工大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.6

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