五神针治疗轻中度痰浊阻窍型血管性痴呆的临床观察

发布时间：2018-08-16 09:26

【摘要】：目的:探讨五神针治疗轻中度痰浊阻窍型血管性痴呆(VD)的临床疗效及安全性。方法:将120例轻中度痰浊阻窍型VD患者按随机数字表法分为基础治疗组、传统针刺组和五神针组,每组40例。基础治疗组给予常规的基础治疗,传统针刺组在基础治疗组治疗基础上取传统针刺穴位进行治疗,五神针组在基础治疗组治疗基础上针刺百会,四神聪为主穴进行治疗,疗程均为36 d。比较各组治疗前后简易精神状态量表(MMSE)、日常生活能力量表(ADL)、痴呆简易筛查量表(BSSD)和VD中医辨证量表痰浊阻窍型分表(中医证候)的评分;检测治疗前后超氧化物歧化酶(SOD)、过氧化脂质(LPO)和丙二醛(MDA)的变化。结果:治疗后五神针组总有效率89.5%,显著高于基础治疗组74.4%(P0.01)和传统针刺组的81.1%(P0.05);五神针组MMSE、ADL、BSSD和中医证候评分较基础治疗组和传统针刺组改善更为显著(均P0.05或P0.01);五神针组SOD、LPO和MDA水平的改善优于基础治疗组和传统针刺组(均P0.05)。结论:五神针组可显著提高痰浊阻窍型血管性痴呆患者的MMSE、ADL、BSSD评分,改善SOD、LPO和MDA的水平,其临床疗效优于基础治疗组和传统针刺组。
[Abstract]:Objective: To explore the clinical efficacy and safety of Wushen acupuncture in the treatment of mild to moderate phlegm turbidity obstructing orifice type vascular dementia (VD).Methods: 120 patients with mild to moderate phlegm turbidity obstructing orifice type VD were randomly divided into basic treatment group, traditional acupuncture group and Wushen acupuncture group, 40 cases in each group. The basic treatment group was treated with traditional acupuncture at acupoints. The Wushen acupuncture group was treated with Baihui and Sishencong for 36 days. The MMSE, ADL, BSSD and VD were compared before and after treatment. Results: After treatment, the total effective rate of Wushen acupuncture group was 89.5%, which was significantly higher than that of the basic treatment group (74.4%) and the traditional acupuncture group (81.1%). Conclusion: Wushen acupuncture group can significantly improve MMSE, ADL, BSSD scores, SOD, LPO and MDA levels in patients with phlegm turbidity obstructing orifice vascular dementia, and improve the levels of SOD, LPO and MDA. The clinical effect was better than that of the basic treatment group and the traditional acupuncture group.
【作者单位】：河南中医药大学针推学院;河南中医药大学第三附属医院针灸科;
【基金】：河南省中医药大学博士科研基金项目(BSJJ2014-21)
【分类号】：R246.6

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