补肾通关颗粒治疗BPH患者临床疗效分析

发布时间：2018-08-22 17:05

【摘要】：目的:探讨补肾通关颗粒辅助治疗良性前列腺增生(BPH)患者的临床疗效。方法:选取2014年1月~2015年12月中南大学湘雅三医院泌尿外科和益阳市第三人民医院收治的120例BPH患者,采用随机数字表法分为观察组和对照组各60例,两组均服用坦索罗辛治疗,观察组加用补肾通关颗粒辅助治疗,疗程均为4周,对比两组临床疗效。结果:治疗后两组患者IPSS、QOL评分及RUV较治疗前均显著降低,Qmax较治疗前显著升高(P0.05),观察组患者IPSS、QOL评分及RUV均显著低于对照组,Qmax显著高于对照组(P0.05);治疗后两组患者夜尿次数、排尿困难、尿线情况、腰膝酸软、少腹胀痛积分均较治疗前显著降低(P0.05),观察组患者夜尿次数、排尿困难、尿线情况、腰膝酸软、少腹胀痛积分均显著低于对照组(P0.05);治疗前治疗后两组间、组内前列腺体积、PSA水平差异均无统计学意义(P0.05);观察组患者治疗愈显率63.33%显著高于对照组的45.00%(P0.05)。结论:补肾通关颗粒辅助治疗BPH患者较单纯西医治疗具有更好的临床疗效。
[Abstract]:Objective: to investigate the clinical effect of Bushen Tongguan granule in the treatment of benign prostatic hyperplasia (BPH). Methods: from January 2014 to December 2015, 120 patients with BPH were selected from the Department of Urology, Xiangya third Hospital of Central South University and the third people's Hospital of Yiyang City. The patients were randomly divided into two groups: the observation group (n = 60) and the control group (n = 60). Both groups were treated with tansoloxine and the observation group were treated with Bushen Tongguan granule for 4 weeks. Results: after treatment, the scores of IPSS QOL and RUV in the two groups were significantly lower than those before treatment (P0.05), the scores of IPSSQOL and RUV in the observation group were significantly lower than those in the control group (P0.05), the number of nocturnal urine in the two groups after treatment was significantly lower than that in the control group (P0.05). Dysuria, urine line, sore waist and knee, less abdominal distending pain score were significantly lower than those before treatment (P0.05). In the observation group, the number of night-urine, dysuria, urethral line, waist and knee were soft and sour. The score of less abdominal distending pain was significantly lower than that of the control group (P0.05); there was no significant difference in prostate volume PSA level between the two groups before and after treatment (P0.05); the curative effect rate of the observation group was 63.33% significantly higher than that of the control group (45.00%) (P0.05). Conclusion: Bushen Tongguan granule is more effective than western medicine in the treatment of BPH.
【作者单位】：中南大学湘雅三医院泌尿外科;益阳市第三人民医院;
【分类号】：R277.5

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