调经系列方周期疗法治疗肾虚型多囊卵巢综合征的临床研究

发布时间：2018-08-25 20:45

【摘要】：研究目的:以肾虚型多囊卵巢综合征的患者为研究对象,通过对调经系列方(二紫方和潮舒煎)周期治疗PCOS患者的临床观察,探究其机理,评价其疗效,为临床治疗PCOS提供理论实践的依据。研究方法:本研究共观察病例60例,年龄在16-40岁患者,均为就诊于河南省中医院妇科门诊患者。采用随机分组,其中治疗组30例,对照组30例,将符合上述纳入标准的治疗组的30例和对照组的30例进行对照。治疗组以调经系列方(二紫方和潮舒煎)治疗,调经系列方(二紫方和潮舒煎)由河南省中医院制剂室制备,煎煮浓缩,每袋200ml,1次1袋,1日2次,早晚温服。对照组以调经促孕丸(产品批号:国药准字Z110200027,生产厂家:北京同仁堂制药厂)和月月舒(产品批号:国药准字Z41021972,生产厂家:河南省宛西制药股份有限公司)治疗,调经促孕丸每日两次,每次1包,月月舒每日两次,每次1包。治疗三月为一疗程,根据病情治疗1个或2个疗程。观察治疗组和对照组的前后临床症状改善情况,检测性激素六项及优势卵泡的情况,空腹血糖及胰岛素的情况判定其临床疗效。结果:治疗组总有效率为86.67%高于对照组的56.67%,两组总体疗效对比,治疗组更优。在改善月经、中医临床症状、提高优势卵泡排出率及提高妊娠率方面,治疗组更优。在降低LH、LH/FSH、T、FINS水平方面,治疗组治疗前和治疗后相差较大,治疗组前后改善要优于对照组。结论:调经系列方周期疗法能够显著改善患者的紊乱内分泌状态,利于月经的规律来潮及尽量避免远期并发症的出现;能够显著提高患者的优势卵泡的数量,增加受孕几率,提升家庭幸福感。在治疗肾虚型PCOS上能够改善临床症状。周期疗法能够更好地调整月经周期,使月经定期而至。
[Abstract]:Objective: to investigate the mechanism of the treatment of PCOS in patients with kidney deficiency polycystic ovary syndrome (PCOS) through clinical observation of Tiaojing series prescription (Erzi Fang and Chaoshu decoction), and to evaluate its curative effect. To provide theoretical and practical basis for clinical treatment of PCOS. Methods: a total of 60 patients aged 16-40 years were observed in this study. They were all outpatients in gynecological clinic of Henan traditional Chinese Medicine Hospital. 30 cases in the treatment group and 30 cases in the control group were randomly divided into two groups: 30 cases in the treatment group and 30 cases in the control group. The treatment group was treated with a series of prescriptions (Erzi recipe and Chaoshu decoction), and a series of prescriptions (Erzi recipe and Chaoshu decoction) were prepared by the preparation room of Henan Provincial Hospital of traditional Chinese Medicine, decoction and concentration, one bag per bag of 200ml, twice a day, warm clothes in the morning and evening. The control group was treated with Tiaojing Cunghong pills (batch number: Z110200027, manufacturer: Beijing Tongrentang Pharmaceutical Factory) and Yueyuesu (batch number: Z41021972, manufacturer: Henan Wanxi Pharmaceutical Co., Ltd). Taijing promoting pregnancy pills twice a day, 1 package each time, month Shu twice a day, 1 pack each time. Treatment for three months as a course of treatment, according to the disease treatment of one or two courses of treatment. The improvement of clinical symptoms before and after treatment group and control group were observed. The six items of sex hormone and the condition of dominant follicle were detected. The condition of fasting blood glucose and insulin was used to judge the clinical curative effect. Results: the total effective rate was 86.67% in the treatment group and 56.67% in the control group. The treatment group is better in improving menstruation, TCM clinical symptoms, improving the rate of dominant follicle excretion and increasing pregnancy rate. In reducing the level of LH,LH/FSH,T,FINS, there was a significant difference before and after treatment in the treatment group, the improvement before and after the treatment group was better than that in the control group. Conclusion: the periodic therapy of regulating menstruation series can significantly improve the disorder endocrine state of patients, facilitate the regular onset of menstruation and avoid the occurrence of long-term complications, increase the number of dominant follicles and increase the probability of conception. Improve family happiness. In the treatment of kidney deficiency PCOS can improve the clinical symptoms. Cycle therapy can better adjust the menstrual cycle, so that menstruation is regular.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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