温通化浊法对冠心病不稳定型心绞痛（痰瘀互结型）纤维蛋白原影响

发布时间：2018-08-27 13:59

【摘要】：目的：运用温通化浊法治疗痰瘀互结型冠心病不稳定型心绞痛,通过观察患者治疗前后中医证候、心电图、血清纤维蛋白原的变化,确定中西医结合治疗冠心病不稳定型心绞痛的临床疗效。方法：选择黑龙江中医药大学附属第一医院心内四科住院符合不稳定型心绞痛(痰瘀互结型)诊断的患者60例,随机分为治疗组和对照组各30例。对照组予以基础治疗,治疗组在治疗基础上,加服中药,每日一剂300m1,早晚两次分服。2周为一个疗程,观察并记录患者治疗前后中医证候积分、心电图疗效、血清纤维蛋白原的变化,所有数据都采用SPSS19.0软件进行统计分析。结果：1.中医临床证候比较：在中医证候有效率方面比较,治疗组优于对照组,有明显性差异(P0.05)；在证候积分方面,治疗后两组数据比较,治疗组优于对照组,有明显性差异(P0.05)。2.心电图疗效比较：治疗组与对照组有效率比较,结果无差异性(P0.05)。总有效率治疗组(66.67%)优于对照组(63.33%)。3.血清纤维蛋白原变化比较：两组治疗后血清纤维蛋白原均较治疗前降低(P0.05);治疗后两组数据比较,治疗组优于对照组,有明显性差异(P0.05)。结论：1.温通化浊法联合基础治疗可改善冠心病不稳定型心绞痛痰瘀互结型患者中医证候。2.温通化浊法联合基础治疗可改善冠心病不稳定型心绞痛痰瘀互结型缺血性心电图ST-T变化。3.温通化浊法联合基础治疗可降低冠心病不稳定型心绞痛痰瘀互结型血清纤维蛋白原水平。
[Abstract]:Objective: to observe the changes of TCM syndromes, electrocardiogram and serum fibrinogen in the treatment of unstable angina pectoris with phlegm and blood stasis syndrome. To determine the clinical efficacy of integrated Chinese and western medicine in the treatment of unstable angina pectoris of coronary heart disease. Methods: sixty patients with unstable angina pectoris (phlegm and blood stasis) were randomly divided into treatment group (n = 30) and control group (n = 30). The control group was treated with basic treatment, the treatment group was treated with traditional Chinese medicine, one dose of 300m1a day, and two times a day for 2 weeks as a course of treatment, observing and recording the TCM syndromes integral and the effect of electrocardiogram before and after treatment. The changes of serum fibrinogen were analyzed by SPSS19.0 software. The result is 1: 1. TCM clinical syndrome comparison: in TCM syndrome effective rate comparison, the treatment group is better than the control group, there is obvious difference (P0.05); in syndromes integral aspect, the treatment group is better than the control group, there is obvious difference (P0.05). Electrocardiogram efficacy comparison: treatment group and control group compared the effective rate, the results were no difference (P0.05). The total effective rate in the treatment group (66.67%) was better than that in the control group (63.33%). Comparison of the changes of serum fibrinogen: after treatment, the serum fibrinogen in both groups was lower than that before treatment (P0.05); after treatment, the treatment group was better than the control group (P0.05). Conclusion 1. Warming and removing turbid method combined with basic treatment can improve TCM syndromes of patients with unstable angina pectoris with phlegm and blood stasis. 2. 2. Warming and removing turbid method combined with basic treatment can improve the change of ST-T of ischemic electrocardiogram in patients with unstable angina pectoris with phlegm and blood stasis. The combination of warming and removing turbid method combined with basic treatment can reduce the level of serum fibrinogen in patients with unstable angina pectoris with phlegm and blood stasis.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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