中药加减龙胆泻肝汤治疗肝火上扰型暴聋的临床观察

发布时间：2018-08-28 16:02

【摘要】：目的:探讨中药加减龙胆泻肝汤治疗暴聋的临床疗效,通过对治疗前后症状积分进行比较,进一步探讨中药对暴聋治疗的有效性,为临床提供更多更好的治疗方法及有效药物。方法:收集2016年1月至2016年12月期间在黑龙江中医药大学附属第一医院耳鼻喉科门诊就诊的突聋患者60例(60耳),以年龄在18-60周岁的患者为观察对象,采取非盲随机区组对照方法,治疗组30例(30耳)和对照组30例(30耳)。治疗组采用中药加减龙胆泻肝汤联合西药凯时注射液静推,维生素B1,维生素B12肌注,对照组仅用西药治疗。7天为一疗程,观察14天后,记录结果并进行统计学分析。所有数据均用SPSS19.0软件进行分析。结果:(1)治疗组总有效率为93.3%,对照组总有效率为86.6%,两组总体疗效经t检验P0.05,有统计学意义。(2)在耳聋、眩晕、烦躁易怒、口苦咽干、胸胁胀痛等症状的改善上,经t检验均P0.05,治疗组比对照组更具优势,统计学有显著差异。在改善耳鸣症状上,经t检验均P0.05,无统计学意义,说明两组疗效相当。结论:(1)中药加减龙胆泻肝汤联合常规西药(凯时、B族维生素注射液)治疗肝火上扰型暴聋较仅仅采用常规西药疗效具有明显的优越性,说明中西医结合治疗优于单纯的西医治疗。(2)中西医结合在耳聋、眩晕、烦躁易怒、口苦咽干、胸胁胀痛等的症状改善上疗效显著,治疗组明显优于对照组。
[Abstract]:Objective: to explore the clinical efficacy of Chinese medicine plus and subtractive Longdan Xiegan decoction in the treatment of deafness and to provide more and better treatment methods and effective drugs for the treatment of deafness by comparing the symptom scores before and after treatment and further exploring the effectiveness of traditional Chinese medicine in the treatment of deafness. Methods: from January 2016 to December 2016, 60 cases (60 ears) of sudden deafness were collected from the otolaryngology clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. 30 cases (30 ears) in the treatment group and 30 cases (30 ears) in the control group were treated with non-blind randomized control group. The treatment group was treated with traditional Chinese medicine plus modified Longdan Xiegan decoction combined with western medicine Keshi injection, vitamin B1 and vitamin B12 were intramuscularly injected, while the control group was treated only with western medicine for 7 days as a course of treatment. After 14 days, the results were recorded and statistically analyzed. All the data were analyzed by SPSS19.0 software. Results: (1) the total effective rate of the treatment group was 93.3g and the total effective rate of the control group was 86.6. The total curative effect of the two groups was significantly improved by t test (P0.05). (2) the improvement of deafness, dizziness, irritability and irritability, dryness of mouth, chest and flank pain, etc. T test showed that the treatment group had more advantages than the control group (P 0.05), and there was significant difference between the treatment group and the control group. In the improvement of tinnitus symptoms, the t test all P 0.05, no statistical significance, indicating that the two groups have the same curative effect. Conclusion: (1) the curative effect of traditional Chinese medicine plus subtractive Longdan Xiegan decoction combined with conventional western medicine (Keshizhuo B vitamin injection) in the treatment of liver fire upstanding deafness is obviously superior to that of only conventional western medicine. The combination of traditional Chinese and western medicine is better than the simple western medicine treatment. (2) the treatment group is better than the control group in the improvement of deafness, vertigo, irritability and irritability, bitter pharynx dry mouth, chest and flank pain and so on.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.1

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