前列5号治疗气滞血瘀型慢性前列腺炎临床疗效观察
发布时间：2018-09-05 10:49
【摘要】：目的:观察前列5号治疗气滞血瘀型慢性前列腺炎的临床疗效材料与方法:参照《中药新药临床研究指导原则》的西医诊断标准和中医症候诊断标准,排除不符的病例,纳入100例符合标准的IIIB型慢性前列腺炎和中医症候为气滞血瘀型慢性前列腺炎患者进行随机对照临床实验,利用抽签法分为治疗组和对照组,每组各50例,治疗组采用自拟前列5号方剂,对照组口服西药可多华和射频治疗物理治疗。两组治疗时间均为4周,并结合美国国立卫生研究院的慢性前列腺炎症状指数(NIH-CPSI)、中医症候量化分级评分以及治疗前后前列腺液中白细胞的变化,观察并分析对比治疗前后两组疗效。进一步验证前列5号治疗气滞血瘀性慢性前列腺炎是较为有效、理想的治疗方法。结果:经过治疗后,治疗组在NIH-CPSI总分、中医症候量化积分优于对照组(P0.05),在单项对比中下腹部坠胀或疼痛和尿后滴沥方面,两组间比较,有极显著差异(P0.01);在会阴部等局部坠胀或疼痛、腰骶部、以及肛门周围坠胀不适或疼痛、尿刺痛方面,两组间比较,有显著差异(P0.05);而在外生殖器区坠胀或疼痛方面,两组间比较,无明显差异(P0.05);而在EPS中WBC变化方面治疗组与对照组无明显差异(P0.05)。结论:治疗组大多数疗效优于对照组,尤其在下腹部坠胀或疼痛和尿后滴沥方面尤为突出,在会阴部等局部坠胀或疼痛、腰骶部以及肛门周围坠胀不适或疼痛、尿刺痛方面,也有较大优势,由此可说明前列5号治疗气滞血瘀型的慢性前列腺炎为有效的治疗方法,值得在临床上推广、应用。
[Abstract]:Objective: to observe the clinical curative effect of Qianlie No. 5 on chronic prostatitis with qi stagnation and blood stasis. A randomized controlled clinical trial was conducted in 100 patients with chronic prostatitis of IIIB type and chronic prostatitis with TCM symptoms of Qi stagnation and Blood stasis. The patients were divided into treatment group and control group with 50 cases in each group by drawing lots. The treatment group was treated with Qianlie No. 5 prescription, while the control group was treated with radiofrequency therapy. The two groups were treated for 4 weeks, combined with the chronic prostatitis symptom index (NIH-CPSI) of the National Institutes of Health (NIH), the quantitative grading of TCM symptoms and the changes of leukocytes in the prostatic fluid before and after treatment. Observe and analyze the curative effect of the two groups before and after treatment. Further verify that Qianlian5 is an effective and ideal treatment for chronic prostatitis caused by stagnation of qi and blood stasis. Results: after treatment, the total score of NIH-CPSI and the quantitative score of TCM symptom in the treatment group were better than those in the control group (P0.05). There was a significant difference (P0.01) between the two groups in local distention or pain in perineum, discomfort or pain in lumbosacral region and perianus, and urinary prickly (P0.05), while in external genital area, there was a significant difference between the two groups in terms of distension or pain. There was no significant difference between the treatment group and the control group (P0.05), but there was no significant difference between the treatment group and the control group in the change of WBC in EPS (P0.05). Conclusion: most of the therapeutic effects in the treatment group are superior to those in the control group, especially in the lower abdominal distention or pain and post-urine drip, especially in the perineal region, in the lumbosacral region and around the anus, in discomfort or pain, and in the urinary prickly. It can be concluded that Qianlie No. 5 is an effective treatment method for chronic prostatitis with Qi stagnation and Blood stasis, which is worth popularizing and applying in clinic.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5
，
本文编号：2224044
[Abstract]:Objective: to observe the clinical curative effect of Qianlie No. 5 on chronic prostatitis with qi stagnation and blood stasis. A randomized controlled clinical trial was conducted in 100 patients with chronic prostatitis of IIIB type and chronic prostatitis with TCM symptoms of Qi stagnation and Blood stasis. The patients were divided into treatment group and control group with 50 cases in each group by drawing lots. The treatment group was treated with Qianlie No. 5 prescription, while the control group was treated with radiofrequency therapy. The two groups were treated for 4 weeks, combined with the chronic prostatitis symptom index (NIH-CPSI) of the National Institutes of Health (NIH), the quantitative grading of TCM symptoms and the changes of leukocytes in the prostatic fluid before and after treatment. Observe and analyze the curative effect of the two groups before and after treatment. Further verify that Qianlian5 is an effective and ideal treatment for chronic prostatitis caused by stagnation of qi and blood stasis. Results: after treatment, the total score of NIH-CPSI and the quantitative score of TCM symptom in the treatment group were better than those in the control group (P0.05). There was a significant difference (P0.01) between the two groups in local distention or pain in perineum, discomfort or pain in lumbosacral region and perianus, and urinary prickly (P0.05), while in external genital area, there was a significant difference between the two groups in terms of distension or pain. There was no significant difference between the treatment group and the control group (P0.05), but there was no significant difference between the treatment group and the control group in the change of WBC in EPS (P0.05). Conclusion: most of the therapeutic effects in the treatment group are superior to those in the control group, especially in the lower abdominal distention or pain and post-urine drip, especially in the perineal region, in the lumbosacral region and around the anus, in discomfort or pain, and in the urinary prickly. It can be concluded that Qianlie No. 5 is an effective treatment method for chronic prostatitis with Qi stagnation and Blood stasis, which is worth popularizing and applying in clinic.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5
，
本文编号：2224044
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