基于医案数据分析的血管性痴呆中医证治规律研究

发布时间：2018-09-14 19:44

【摘要】：目的:通过统计软件对中医治疗血管性痴呆医案的证候、治则、药物进行分析,从而探索血管性痴呆的中医辨证论治规律,进而更好的指导临床应用,并为进一步研究提供参考。方法:1.进入“百链”网站搜索页面,以“血管性痴呆+案”作为检索的词组,检索结果为611条,筛选符合条件的医案78条;以“血管性痴呆+经验”为检索词,检索结果为1194条,筛选符合条件的医案35条。以113条血管性痴呆的中医医案作为研究材料。2.将113条医案里记载的中医证型、治法、使用药物逐一输入中医传承辅助系统软件,再次校验输入信息的正确性,并保存备用。3.运用中医传承辅助系统软件中的统计报表系统和数据分析系统进行相关数据的统计分析,并将所得的证候、治则、药物频次,以及核心药对、新处方数据导出保存。结果:1.血管性痴呆医案中的主要中医辨证类型为痰瘀阻窍证、瘀血阻络证、痰浊阻窍证、肾精亏虚证、髓海不足证。2.血管性痴呆医案中常用化痰开窍、活血化瘀、补肾益髓、醒脑开窍、益气活血的治疗原则。3.血管性痴呆医案共使用中药224味,其中使用频率最高的中药依次为石菖蒲、远志、川芎、茯苓、丹参,并确定了药物的关联规则及关联程度。4.通过中医传承辅助系统软件运用聚类分析方法对113条血管性痴呆医案挖掘出了12组核心药对,进一步在核心药对的基础上演化出6个新处方。结论:1.血管性痴呆的中医辨证多为“痰”、“瘀”、“虚”,治疗原则、常用中药与辨证相吻合。2.运用数据挖据的方法,把个别中医经验与中医传承辅助系统平台对医案的集成研究结合起来,获得了中医治疗血管性痴呆的辨证论治规律。3.通过中医传承辅助系统软件对临床治疗经验进行分析的结果具有一定的科学性,对于指导临床及基础应用研究具有重要作用。
[Abstract]:Objective: to analyze the syndromes, principles and drugs of traditional Chinese medicine (TCM) in the treatment of vascular dementia by statistical software, so as to explore the law of syndrome differentiation and treatment of vascular dementia, and to guide the clinical application better. It also provides reference for further study. Method 1: 1. Enter the search page of "hundred chain" website, take "vascular dementia case" as the search phrase, search result is 611, screen 78 qualified medical cases, take "vascular dementia experience" as key word, search result is 1194, 35 articles of qualified medical records were screened. 113 cases of vascular dementia were used as the research materials. 2. 2. 113 cases of TCM syndrome type, treatment methods, the use of drugs one by one into the Chinese medicine heritage assistance system software, again check the correctness of input information, and save spare .3. The statistical report system and data analysis system in the software of traditional Chinese medicine heritage assistant system are used to carry on the statistical analysis of relevant data, and the data of syndrome, treatment rule, drug frequency, core drug pair and new prescription are exported and preserved. The result is 1: 1. The main types of TCM syndrome differentiation in vascular dementia cases are phlegm stasis syndrome, blood stasis syndrome, phlegm stagnation syndrome, kidney essence deficiency syndrome, marrow sea deficiency syndrome. Vascular dementia commonly used in the medical records of phlegm resuscitation, blood circulation, tonifying kidney and marrow, waking up the brain and opening the orifices, invigorating qi and activating blood circulation treatment principle. 3. Vascular dementia cases used 224 Chinese medicine, in which the highest frequency of use of traditional Chinese medicine is Acorus calamus, Radix Polygala, Ligusticum chuanxiong, Poria cocos, Salvia miltiorrhiza, and determined the drug association rules and correlation degree. 4. Twelve groups of core drug pairs were excavated from 113 cases of vascular dementia by using the software of traditional Chinese Medicine inheritance Assistance system, and 6 new prescriptions were further developed on the basis of core drug pairs. Conclusion 1. The traditional Chinese medicine differentiation of vascular dementia is mostly "phlegm", "stasis", "deficiency", treatment principle. By using the method of data digging, combining the experience of individual TCM with the integrated research of medical records based on the platform of traditional Chinese Medicine (TCM) inheritance Assistant system, the law of syndrome differentiation and treatment of vascular dementia by TCM was obtained. It is scientific to analyze the clinical experience through the software of traditional Chinese Medicine (TCM) inheritance Assistant system, which is important for guiding clinical and basic application research.
【学位授予单位】：河北大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.7

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