不稳定型心绞痛中医证型与CAG结果及血脂水平等因素的相关性研究

发布时间：2018-10-05 07:20

【摘要】：目的:通过收集患者的基本信息、四诊资料、CAG结果、血脂水平等相关资料,分析冠心病不稳定型心绞痛中医证型与CAG结果及血脂水平等因素的相关关系,为中医防治本病提供依据。方法:收集2016年2月—2016年6月于中国医科大学附属盛京医院心内科住院病例122例,行CAG检查前进行中医辨证分型,通过采取空腹前臂静脉血浆,测定TG、TC、HDL、LDL的数值,根据冠状动脉病变情况计算Gensini评分,利用统计软件分析中医证型与各项指标的相关关系。结果:1、120例患者中女性平均年龄大于男性平均年龄;2、各危险因素的分布频次依次为高血压吸烟饮酒脂质代谢异常糖尿病或糖耐量异常;3、实证组Gensini评分平均值虚证组Gensini评分平均值,心血瘀阻证患者的Gensini评分平均值明显大于其它证型组患者的Gensini评分平均值,P0.05,有统计学意义;4、痰阻心脉证患者的血脂水平明显高于其它证型的患者,P0.05,有统计学意义。结论:1、不稳定型心绞痛多发于中老年人,男性患者数量多于女性患者数量,且随着年龄的增长,女性患者数量逐渐增加;2、不稳定型心绞痛发病的危险因素从高到低依次为,高血压、吸烟、饮酒、脂质代谢异常、糖尿病或糖耐量异常;3、不稳定型心绞痛实证组患者的冠脉病变程度较虚证组患者的冠脉病变程度重,心血瘀阻证患者的冠脉病变程度明显大于其他五组患者;4、不稳定型心绞痛患者中痰阻心脉证患者的血脂水平最高。
[Abstract]:Objective: to analyze the correlation between TCM syndrome type of unstable angina pectoris of coronary heart disease (CHD), CAG result and blood lipid level by collecting the basic information of the patients, the data of four diagnoses and the results of CAG, the level of blood lipid and so on. To provide the basis for TCM prevention and treatment of this disease. Methods: from February 2016 to June 2016, 122 cases of cardiology hospitalized in Shengjing Hospital affiliated to China Medical University were collected. Before CAG examination, TCM syndrome differentiation was carried out, and fasting forearm venous plasma was taken to determine the value of TG,TC,HDL,LDL. The Gensini score was calculated according to coronary artery disease, and the correlation between TCM syndrome types and various indexes was analyzed by statistical software. Results the average age of female was larger than that of male, and the distribution frequency of each risk factor was hypertension, smoking, drinking, abnormal lipid metabolism, diabetes mellitus or abnormal glucose tolerance. The average Gensini score of positive group was the average of Gensini score in deficiency syndrome group. The average value of Gensini score in patients with heart blood stasis syndrome was significantly higher than that in other syndrome groups (P 0.05, P 0.05). The blood lipid level of patients with phlegm blocking heart and pulse syndrome was significantly higher than that of patients with other syndrome types (P 0.05). Conclusion the number of male patients with unstable angina pectoris is more than that of female patients, and the number of female patients increases gradually with the increase of age. The risk factors of unstable angina pectoris are from high to low. Hypertension, smoking, drinking, abnormal lipid metabolism, diabetes mellitus or impaired glucose tolerance. The severity of coronary artery disease in patients with unstable angina pectoris was higher than that in patients with deficiency syndrome. The degree of coronary artery lesion in the patients with heart blood stasis syndrome was significantly higher than that in the other five groups, and the blood lipid level was the highest in the patients with unstable angina pectoris.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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