宫血停方治疗围绝经期肾阴亏虚型崩漏的临床观察

发布时间：2018-10-10 14:16

【摘要】：目的：本课题采用宫血停方治疗围绝经期肾阴亏虚型崩漏患者,并与对照组(炔诺酮片)比较,观察治疗后患者阴道出血、中医症状、血红蛋白及月经的改善情况,客观评价两种治疗方法的疗效差异。方法：选择60例符合标准的诊刮术后一周仍见阴道不规则出血的围绝经期肾阴亏虚型崩漏患者,按随机数字表法分为治疗组.(宫血停方组)、对照组(炔诺酮片组)各30例。观察两组治疗后阴道出血情况及治疗3个月经周期后的中医症状改善情况、两组停药后3个月的月经情况、并测定治疗前后血红蛋白含量的变化情况。最后进行统计学处理及分析。结果：1.治疗组总有效率80.00%；对照组总有效率83.33%。两组患者综合疗效比较,差异无统计学意义(P0.05),表明两组综合疗效相当。2.两组患者治疗后与各自治疗前症状总积分比较,均有显著性差异(P0.05)；两组患者治疗后组间症状总积分比较,差异有显著性意义(P0.05)；表明治疗组在改善中医症状方面优于对照组。3.两组患者治疗后阴道止血情况比较,差异无统计学意义(P0.05),表明治疗组与对照组在阴道止血疗效上相当。4.两组患者治疗后与各自治疗前血红蛋白含量的变化比较,有显著性差异(P0.05)；两组患者治疗后组间血红蛋白含量比较,差异有显著性意义(P0.05)；表明治疗组在提高血红蛋白含量方面优于对照组。5.两组治疗后随访3个月的组间月经情况比较,差异均有显著性意义(P0.05),表明治疗组的远期调经疗效优于对照组。结论：采用中医药辨证施治“澄源、复旧”是治崩的延续,运用宫血停方治疗围绝经期肾阴亏虚型崩漏患者,对于远期调经疗效较有优势,从而提高治疗效果及降低复发率。
[Abstract]:Objective: to observe the improvement of vaginal bleeding, symptoms of traditional Chinese medicine, hemoglobin and menstruation in patients with peri-menopausal kidney yin deficiency type insipidus treated with Gong Xue stopping prescription, and compared with control group (norethisterone tablet). Objective to evaluate the difference of therapeutic effect between the two methods. Methods: sixty cases of peri-menopausal kidney yin deficiency type with irregular vaginal bleeding one week after curettage were selected and randomly divided into treatment group. (Gongxue stopping prescription group), control group (norethisterone tablet group) 30 cases each. The vaginal bleeding after treatment and the improvement of TCM symptoms after 3 menstrual cycles were observed in the two groups. The menstruation of the two groups after 3 months' withdrawal was observed and the changes of hemoglobin content before and after treatment were measured. Finally, statistical processing and analysis are carried out. The result is 1: 1. The total effective rate was 80.00in the treatment group and 83.33g in the control group. Two groups of patients comprehensive efficacy comparison, the difference is not statistically significant (P0.05), indicating that the two groups of comprehensive efficacy is equivalent. 2. Two groups of patients after treatment and their symptoms before the total score, there were significant differences (P0.05); two groups of patients after treatment, the total symptom score comparison, significant difference (P0.05); show that the treatment group in improving TCM symptoms than the control group. 3. There was no significant difference between the two groups in vaginal hemostasis after treatment (P0.05), indicating that the treatment group and the control group in the vaginal hemostatic efficacy was equivalent. 4. There was significant difference in hemoglobin content between the two groups after treatment and before treatment (P0.05), and there was significant difference in hemoglobin content between the two groups after treatment (P0.05). The results showed that the treatment group was superior to the control group in increasing hemoglobin content. There were significant differences in menstruation between the two groups after 3 months follow-up (P0.05), which indicated that the long-term menstrual adjustment effect in the treatment group was better than that in the control group. Conclusion: the treatment of "Chengyuan, restoring old" by TCM differentiation is the continuation of the treatment of avalanche. The treatment of peri-menopausal patients with deficiency of kidney yin and deficiency of kidney yin by using Gongxue stopping prescription has an advantage in long-term menstrual regulation, thus improving the therapeutic effect and reducing the recurrence rate.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.12

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