和解安神方治疗失眠症（肝郁脾虚型）的临床疗效观察

发布时间：2018-10-14 19:15

【摘要】：目的:观察和解安神方治疗失眠症(肝郁脾虚型)的临床疗效;总结导师临床经验,为失眠症(肝郁脾虚型)的治疗提供新的思维方法,为临床应用和解安神方治疗失眠症(肝郁脾虚型)提供依据。方法:将符合纳入标准的72例患者随机分两组,试验组36例采用和解安神方治疗;对照组36例予右佐匹克隆口服治疗;疗程均为4周。治疗结束后对两组的临床疗效进行对比。经过4周治疗后,观察两组总体疗效,评估患者失眠情况并进行对比分析,发放问卷评估患者主观治疗有效率,并且将所有观察记录数据采用SPSS17.0统计软件分析数据。结果:两组患者的年龄、性别等基本情况无明显差异(P0.05)。研究过程中,排除终止试验及脱落失访患者,最终剩余67人完成本试验(试验组33人,对照组34人)。试验组总有效率90.90%,高于对照组总有效率76.47%,试验组与对照组相比较,差异有显著性意义(P0.05)。试验组仅1例出现便溏,药物加减调整后正常,不良反应发生率为2.33%。对照组日间困倦4例,出现口干、口苦症状3例,出现头晕、头痛症状1例,不良反应发生率为18.60%。试验组与对照组不良反应发生率比较,差异有显著性意义(P0.05)。结论:服用和解安神方治疗失眠证(肝郁脾虚型)的治疗效果比口服右佐匹克隆的治疗效果显著。用和解安神方治疗失眠证(肝郁脾虚型),能有效改善患者睡眠质量,改善患者兼次症状,减轻患者抑郁焦虑状态,提高生活质量。
[Abstract]:Objective: to observe the clinical curative effect of Heunanshen recipe in the treatment of insomnia (liver depression and spleen deficiency type), summarize the clinical experience of tutor, and provide a new thinking method for the treatment of insomnia (liver stagnation and spleen deficiency type). To provide the basis for clinical application of Heunanshen recipe in the treatment of insomnia (liver stagnation and spleen deficiency type). Methods: 72 patients who met the inclusion criteria were randomly divided into two groups: the experimental group (n = 36) was treated with Heanan Shen Fang (n = 36) and the control group (n = 36) by oral administration of right zopicone. The course of treatment was 4 weeks. The clinical effects of the two groups were compared after treatment. After 4 weeks of treatment, we observed the overall curative effect of the two groups, evaluated the insomnia of the patients and carried on the comparative analysis, distributed the questionnaire to evaluate the effective rate of subjective treatment of the patients, and used the SPSS17.0 statistical software to analyze all the observed data. Results: there was no significant difference in age, sex and other basic conditions between the two groups (P0.05). In the course of the study, the patients were excluded from the termination test and dropped off, and the remaining 67 patients completed the trial (33 patients in the trial group and 34 patients in the control group). The total effective rate of the experimental group was 90.90, which was higher than that of the control group (76.477.Compared with the control group, the difference was significant (P0.05). In the test group, there was only one case with loose stools, and the incidence of adverse reactions was 2.33%. In the control group, there were 4 cases of daytime sleepiness, 3 cases of dry mouth, 3 cases of bitter mouth symptoms, 1 case of dizziness and 1 case of headache. The incidence of adverse reaction was 18.60%. There was a significant difference in the incidence of adverse reactions between the experimental group and the control group (P0.05). Conclusion: the curative effect of the treatment of insomnia syndrome (liver depression and spleen deficiency type) by taking Heunanshen recipe is more effective than that of taking right zopicone orally. The treatment of insomnia syndrome (liver depression and spleen deficiency type) with reconciliation and Anshen prescription can effectively improve the sleep quality of the patients, improve the concurrent symptoms of the patients, alleviate the depression and anxiety of the patients, and improve the quality of life.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.23

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