补肾培元毓麟汤治疗子宫内膜损伤继发不孕症患者48例临床观察
发布时间：2018-10-16 15:08
【摘要】：目的观察自拟补肾培元毓麟汤治疗子宫内膜损伤继发性不孕症患者的临床疗效。方法将97例子宫内膜损伤的继发性不孕症患者按其自身意愿分为中药组51例和对照组46例,中药组于月经第5天开始给予自拟补肾培元毓麟汤,经期停药;对照组于月经第5天开始口服戊酸雌二醇片,排卵后加服地屈孕酮片,两组均治疗6个月经周期。治疗后分别比较两组患者的6个月内妊娠率和妊娠者20周时的通过率及妊娠结局,对于未妊娠患者比较其子宫内膜厚度、月经量的改变及临床总有效率。结果中药组患者6个月内妊娠率为54.17%,明显高于对照组的30.77%,且保胎至孕20周通过率为92.31%明显高于对照组的58.33%(P0.05)。两组患者治疗后均较治疗前的月经量增多、子宫内膜增厚,且中药组月经量改善程度优于对照组(P0.05或P0.01)。中药组的总有效率为93.75%,优于对照组的74.31%(P0.05)。结论补肾培元毓麟汤对于提高子宫内膜损伤的继发性不孕症患者的妊娠率有较好的疗效,并且可改善此类患者的月经量及子宫内膜厚度。
[Abstract]:Objective to observe the clinical effect of Bushen Peiyuan Yulin decoction in treating infertility secondary to endometrial injury. Methods 97 cases of secondary infertility with endometrial injury were divided into Chinese medicine group (51 cases) and control group (46 cases) according to their own wishes. The control group began to take estradiol valerate tablets on the 5th day of menstruation, then ovulated with diproprogesterone tablets. Both groups were treated for 6 menstrual cycles. After treatment, the pregnancy rate within 6 months and the pregnancy outcome at 20 weeks were compared between the two groups, and the endometrial thickness, menstrual volume and the total clinical effective rate were compared for the patients without pregnancy. Results the pregnancy rate in the Chinese medicine group was 54.17, which was significantly higher than that in the control group (30.77%), and the pass rate from fetal protection to 20 weeks gestation was 92.31%, which was significantly higher than that in the control group (58.33%) (P0.05). After treatment, the menstrual volume and endometrial thickness of the two groups were increased, and the improvement degree of menstrual volume in the Chinese medicine group was better than that in the control group (P0.05 or P0.01). The total effective rate of TCM group was 93.75, which was better than that of control group (74.31%, P0.05). Conclusion Bushen Peiyuan Yulin decoction has a good effect on improving the pregnancy rate of patients with secondary infertility with endometrial injury, and can improve the menstrual volume and endometrial thickness of these patients.
【作者单位】： 上海中医药大学附属龙华医院;
【基金】：上海市卫生和计划生育委员会科研项目(201440028)
【分类号】：R271.14
本文编号：2274736
[Abstract]:Objective to observe the clinical effect of Bushen Peiyuan Yulin decoction in treating infertility secondary to endometrial injury. Methods 97 cases of secondary infertility with endometrial injury were divided into Chinese medicine group (51 cases) and control group (46 cases) according to their own wishes. The control group began to take estradiol valerate tablets on the 5th day of menstruation, then ovulated with diproprogesterone tablets. Both groups were treated for 6 menstrual cycles. After treatment, the pregnancy rate within 6 months and the pregnancy outcome at 20 weeks were compared between the two groups, and the endometrial thickness, menstrual volume and the total clinical effective rate were compared for the patients without pregnancy. Results the pregnancy rate in the Chinese medicine group was 54.17, which was significantly higher than that in the control group (30.77%), and the pass rate from fetal protection to 20 weeks gestation was 92.31%, which was significantly higher than that in the control group (58.33%) (P0.05). After treatment, the menstrual volume and endometrial thickness of the two groups were increased, and the improvement degree of menstrual volume in the Chinese medicine group was better than that in the control group (P0.05 or P0.01). The total effective rate of TCM group was 93.75, which was better than that of control group (74.31%, P0.05). Conclusion Bushen Peiyuan Yulin decoction has a good effect on improving the pregnancy rate of patients with secondary infertility with endometrial injury, and can improve the menstrual volume and endometrial thickness of these patients.
【作者单位】： 上海中医药大学附属龙华医院;
【基金】：上海市卫生和计划生育委员会科研项目(201440028)
【分类号】：R271.14
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1 邵梦秋;张良英教授助孕方对人流术后子宫内膜损伤继发不孕的临床研究[D];广州中医药大学;2014年
，本文编号：2274736
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