五加安神饮治疗心肾不交型不寐的临床观察

发布时间：2018-10-16 16:45

【摘要】：目的:本课题通过临床观察五加安神饮治疗心肾不交型不寐患者的临床疗效,并对其治疗机理进行讨论,以期为中医临床治疗不寐提供新的思路。方法:收集50例心肾不交型不寐患者随机分为治疗组、对照组各25例。治疗组口服五加安神饮,对照组口服乌灵胶囊,疗程为28天。以匹兹堡睡眠质量指数(PSQI)评分、中医证候积分为临床观察指标,评价五加安神饮治疗心肾不交型不寐的临床疗效。结果:经治疗两个疗程后,治疗组总有效率、PSQI积分、中医证候积分均优于对照组,两组比较差异有统计学意义(P0.05)。说明治疗组在改善睡眠质量及中医证候方面疗效优于对照组。两组治疗后及随访3个月后总有效率进行比较,治疗组差异无统计学意义(P0.05);对照组差异有统计学意义(P0.05)。说明治疗组远期疗效稳定,优于对照组。结论:五加安神饮能明显改善心肾不交型不寐患者的睡眠质量及中医证候且远期疗效稳定。
[Abstract]:Objective: to observe the clinical effect of Wujia Anshenyin in treating insomnia of heart and kidney disjoint type and discuss its therapeutic mechanism in order to provide new ideas for clinical treatment of insomnia in traditional Chinese medicine. Methods: 50 patients with heart-kidney disjoint insomnia were randomly divided into treatment group (n = 25) and control group (n = 25). The treatment group was treated with Wujia Anshen decoction and the control group with Wuling capsule for 28 days. To evaluate the clinical efficacy of Wujia Anshen Yin in treating insomnia of heart and kidney disjoint type, Pittsburgh Sleep quality Index (PSQI) score and TCM syndrome score were used as clinical observation index. Results: after two courses of treatment, the total effective rate, PSQI score and TCM syndrome score in the treatment group were better than those in the control group, and the difference between the two groups was statistically significant (P0.05). It showed that the therapeutic effect of the treatment group was better than that of the control group in improving sleep quality and TCM syndrome. After treatment and follow up for 3 months, the total effective rate of the two groups were compared, the difference of the treatment group was not statistically significant (P0.05), the difference of the control group was statistically significant (P0.05). It indicated that the long-term curative effect of the treatment group was stable and superior to the control group. Conclusion: Wujia Anshen decoction can obviously improve sleep quality and TCM syndrome of patients with insomnia of heart and kidney disjoint type, and the long term curative effect is stable.
【学位授予单位】：黑龙江省中医药科学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R256.23

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