益气逐瘀通络汤治疗气虚血瘀型稳定性心绞痛的临床疗效观察及对运动耐量的影响
发布时间：2018-10-18 08:54
【摘要】：目的:本试验旨在观察益气逐瘀通络汤对气虚血瘀型稳定性心绞痛患者的临床疗效及对运动耐量的影响。方法:将入选的60例稳定性心绞痛(气虚血瘀型)患者,采用随机、对照原则,分为对照组和治疗组,每组各30例。对照组采用西医常规治疗,治疗组在此基础上加服益气逐瘀通络汤。疗程为4周,对比观察两组患者的心绞痛积分、心绞痛疗效、中医证候积分、中医证候疗效、硝酸甘油停减率、运动耐量(总运动时间、代谢当量、出现ST段压低1mm的时间、心绞痛出现时间)的变化,运用统计学软件处理相应数据并进行结果分析。结果:1.治疗后,经统计学检验,两组的心绞痛症状积分、中医证候积分方面均较治疗前均明显降低(P0.05),且治疗组上述指标明显低于对照组(P0.05),差异均有统计学意义。2.治疗后,经统计学检验,两组的心绞痛疗效相比,治疗组为86.67%,对照组为63.33%(P0.05);中医证候疗效相比,治疗组为83.33%,对照组为56.67%(P0.05);硝酸甘油停减率相比,治疗组为90.00%,对照组为70.00%(P0.05),差异均有统计学意义。3.治疗后,经统计学检验,两组的代谢当量较治疗前明显提高;总运动时间、ST段压低1mm的时间、心绞痛出现时间均较治疗前明显延长(P0.05),且治疗组上述指标明显优于对照组(P0.05),差异均有统计学意义。结论:1.益气逐瘀通络汤能明显改善气虚血瘀型稳定性心绞痛患者的症状及减少硝酸甘油的用量。2.益气逐瘀通络汤能提高气虚血瘀型稳定性心绞痛患者的运动耐量。
[Abstract]:Objective: to observe the effect of Yiqi Zhuyu Tongluo decoction on stable angina pectoris with qi deficiency and blood stasis and its effect on exercise tolerance. Methods: sixty patients with stable angina pectoris (Qi deficiency and blood stasis type) were randomly divided into control group and treatment group with 30 cases in each group. The control group was treated with routine western medicine, and the treatment group was treated with Yiqi Zhuyu Tongluo decoction. The course of treatment was 4 weeks. The score of angina pectoris, the curative effect of angina pectoris, the integral of TCM syndromes, the curative effect of TCM syndromes, the stopping and decreasing rate of nitroglycerin, the exercise tolerance (total exercise time, metabolic equivalent, the time of ST segment depression 1mm) were compared between the two groups. The time of occurrence of angina pectoris was analyzed by statistical software. The result is 1: 1. After treatment, after the statistical test, the two groups of angina pectoris symptom score, TCM syndrome score were significantly lower than before treatment (P0.05), and the treatment group was significantly lower than the control group (P0.05), the difference was statistically significant. After treatment, the therapeutic effect of angina pectoris was 86.67% in the treatment group, 63.33% in the control group (P0.05), 83.33% in the treatment group and 56.67% (P0.05) in the control group. The treatment group was 90.00g and the control group was 70.00% (P0.05), the difference was statistically significant. After treatment, the metabolic equivalent of the two groups was significantly higher than that before treatment, the total exercise time, the time of ST segment depression of 1mm, Angina pectoris appeared time was significantly longer than before treatment (P0.05), and the treatment group was significantly better than the control group (P0.05), the difference was statistically significant. Conclusion: 1. Yiqi Zhuyu Tongluo decoction can obviously improve the symptoms of stable angina patients with Qi deficiency and blood stasis type and reduce the dosage of nitroglycerin. 2. Yiqi Zhuyu Tongluo decoction can improve the exercise tolerance of stable angina pectoris with qi deficiency and blood stasis.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259
本文编号：2278628
[Abstract]:Objective: to observe the effect of Yiqi Zhuyu Tongluo decoction on stable angina pectoris with qi deficiency and blood stasis and its effect on exercise tolerance. Methods: sixty patients with stable angina pectoris (Qi deficiency and blood stasis type) were randomly divided into control group and treatment group with 30 cases in each group. The control group was treated with routine western medicine, and the treatment group was treated with Yiqi Zhuyu Tongluo decoction. The course of treatment was 4 weeks. The score of angina pectoris, the curative effect of angina pectoris, the integral of TCM syndromes, the curative effect of TCM syndromes, the stopping and decreasing rate of nitroglycerin, the exercise tolerance (total exercise time, metabolic equivalent, the time of ST segment depression 1mm) were compared between the two groups. The time of occurrence of angina pectoris was analyzed by statistical software. The result is 1: 1. After treatment, after the statistical test, the two groups of angina pectoris symptom score, TCM syndrome score were significantly lower than before treatment (P0.05), and the treatment group was significantly lower than the control group (P0.05), the difference was statistically significant. After treatment, the therapeutic effect of angina pectoris was 86.67% in the treatment group, 63.33% in the control group (P0.05), 83.33% in the treatment group and 56.67% (P0.05) in the control group. The treatment group was 90.00g and the control group was 70.00% (P0.05), the difference was statistically significant. After treatment, the metabolic equivalent of the two groups was significantly higher than that before treatment, the total exercise time, the time of ST segment depression of 1mm, Angina pectoris appeared time was significantly longer than before treatment (P0.05), and the treatment group was significantly better than the control group (P0.05), the difference was statistically significant. Conclusion: 1. Yiqi Zhuyu Tongluo decoction can obviously improve the symptoms of stable angina patients with Qi deficiency and blood stasis type and reduce the dosage of nitroglycerin. 2. Yiqi Zhuyu Tongluo decoction can improve the exercise tolerance of stable angina pectoris with qi deficiency and blood stasis.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259
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