湿疹2号方治疗血虚风燥型湿疹的临床疗效研究

发布时间：2018-10-29 11:38

【摘要】：目的:通过对1年来,辽宁中医药大学附属医院皮肤科门诊的血虚风燥型湿疹患者进行临床观察,研究湿疹2号方的临床疗效。材料与方法:本次选取的患者共63例,均来自于2013年12月—2014年9月就诊于辽宁中医药大学附属医院皮肤科门诊,经中医辨证为血虚风燥型湿疹,符合纳入标准,按照随机表法分为治疗组(湿疹2号方)和对照组(润燥止痒胶囊),两组均外用湿疹洗剂(自拟),治疗组32例,对照组31例。实验室检查包括:心电图,血尿常规,肝肾功能,嗜酸粒细胞计数和血清总IgE,疗程为60±2天。运用统计学方法对疗效、皮肤损害指标、瘙痒程度、相关化验指标等进行分析。结果:1.两组临床疗效比较,经秩和检验P0.05,湿疹2号总有效率为93.33%,润燥止痒胶囊总有效率为73.33%,治疗组疗效优于对照组。2.皮损面积治疗后两组进行比较,经秩和检验,P0.05,表明湿疹2号可减少湿疹的皮损面积。3.皮损形态治疗后两组进行比较,经t检验,P0.05,表明湿疹2号可改善红斑、脱屑、干燥、肥厚和皲裂等皮损状态。4.瘙痒程度治疗后两组进行比较,经秩和检验,P0.05,表明湿疹2号可缓解患者的瘙痒症状。5.嗜酸粒细胞计数和总IgE治疗前后比较,经秩和检验,P0.05,表明治疗前后差别不明显。治疗前后两组嗜酸粒细胞计数有改善的各占18.33%,20%;两组总IgE组有改善的各占31.67%和50%。结论:1.湿疹2号方治疗血虚风燥型湿疹优于对照组。2.湿疹2号方结合湿疹洗剂可改善皮肤受损的状态,并能显著缓解患者的自觉症状。3.湿疹2号方和润燥止痒胶囊均可在一定程度上可改善嗜酸性粒细胞计数和血清总IgE指标。
[Abstract]:Objective: to study the clinical effect of prescription No. 2 on eczema of blood deficiency and wind dryness type in dermatology department of affiliated Hospital of Liaoning University of traditional Chinese Medicine (Liaoning University of traditional Chinese Medicine) for one year. Materials and methods: a total of 63 patients from December 2013 to September 2014 were admitted to the Department of Dermatology, affiliated Hospital of Liaoning University of traditional Chinese Medicine. According to the random table method, the treatment group (eczema 2) and the control group (Runzao Zhitao capsule) were divided into treatment group (32 cases) and control group (31 cases). Both groups were treated with external eczema lotion (self-made). Laboratory examination included electrocardiogram, routine blood and urine routine, liver and kidney function, eosinophil count and total serum IgE, for 60 卤2 days. Statistical method was used to analyze the curative effect, skin damage index, pruritus degree and related test index. The result is 1: 1. The total effective rate of eczema 2 was 93.33 and the total effective rate of Runzao Zhiyang capsule was 73.33. The curative effect of the treatment group was better than that of the control group. 2. The results of rank sum test showed that eczema No. 2 could reduce the area of eczema. The results showed that eczema No. 2 could improve the lesion state of erythema, desquamation, dryness, hypertrophy and chapped by t test (P0.05). The degree of pruritus was compared between the two groups after treatment, and the rank sum test, P0.05, showed that eczema No. 2 alleviated itching symptoms in patients. 5. 5%. The number of eosinophils was compared with that of total IgE before and after treatment, and the rank sum test showed that there was no significant difference before and after treatment (P 0.05). The percentage of eosinophils in the two groups improved 18.3320% before and after treatment and 31.67% and 50% in the total IgE group respectively. Conclusion: 1. The treatment of eczema 2 was superior to that of the control group in the treatment of eczema with blood deficiency and wind dryness. 2. Side 2 of eczema combined with eczema lotion can improve the condition of skin damage, and can significantly relieve the conscious symptoms of patients. Eczema 2 prescription and Runzao Zhiyang capsule can improve eosinophil count and serum total IgE index to some extent.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9
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本文编号：2297582