基于数据挖掘的陈镜合治疗心悸用药规律研究

发布时间：2018-11-04 13:30

【摘要】：目的:基于"中医传承辅助平台"(V2.5)软件,对陈镜合教授临证治疗心悸的用药规律进行分析。方法:以陈镜合在广州中医药大学第一附属医院2014年3月至2016年1月岭南名医门诊治疗心悸病例为研究对象,提取处方药物建立数据库,采用关联规则、改进的互信息法、复杂系统熵聚类等数据挖掘方法分析其治疗心悸的用药规律。结果:共纳入处方400首,使用药物总计160味,其中高频使用药物的前三位为甘草、茯苓、党参,高频药物组合前三位的为"甘草-茯苓""党参-甘草""陈皮-甘草",并挖掘出10首聚类新处方。结论:陈镜合教授治疗心悸立足于脾,以理脾治心为大法,临证多以六君子汤为基础方加减,并根据合并有肝郁气滞、痰火扰心、气阴两虚、阴虚火旺、心阳不振等兼证灵活化裁,多合用四逆散、温胆汤、生脉散、百合地黄汤、桂甘龙牡汤等。
[Abstract]:Objective: based on the software of "traditional Chinese Medicine inheritance Assistance platform" (V2.5), this paper analyzes the drug use of Professor Chen Jinghe in the treatment of palpitation. Methods: from March 2014 to January 2016, Chen Jinghe was selected from the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine for the treatment of palpitation cases in Lingnan famous Medical Clinic. The prescription drugs were extracted to establish a database, and the association rules and improved mutual information method were used. Data mining methods such as entropy clustering of complex systems were used to analyze the drug use in the treatment of palpitation. Results: a total of 400 prescriptions were included and a total of 160 drugs were used. Among them, the top three were liquorice, Poria cocos, Codonopsis pilosula, and the first three high frequency drug combinations were "liquorice and Poria cocos", "Codonopsis licorice" and "Chenpi liquorice". Ten new prescriptions for clustering were excavated. Conclusion: professor Chen Jinghe's treatment of palpitation is based on the spleen, treating the heart with the liver-spleen and treating the heart as the great method, the clinical syndrome is based on the decoction of six Gentlemen, and according to the combination of liver depression and qi stagnation, phlegm and fire disturbing the heart, qi and yin deficiency, Yin deficiency and fire flourishing, Heart Yang and other syndrome flexible cut, more use of Sinisan, Wendan decoction, Shengmai San, Lily Dihuang decoction, Gui Gan long Mu Tang, and so on.
【作者单位】：广州中医药大学第一临床医学院;广州中医药大学第一附属医院;
【基金】：国家中医药管理局全国名老中医药专家陈镜合传承工作室建设项目(国中医药人教发[2011]41号)
【分类号】：R249;R256.21

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