自拟排石颗粒联合ESWL治疗湿热蕴结型输尿管结石临床回顾

发布时间：2018-11-07 09:38

【摘要】：目的:本文旨在观察我院自拟排石颗粒联合体外冲击波碎石术治疗湿热蕴结型输尿管结石的临床疗效,探讨自拟排石颗粒对体外冲击波碎石术后输尿管结石治愈率、总有效率等的影响。材料与方法:本研究采用回顾性分析方法,选取2015年1月至2016年1月期间辽宁省中医院泌尿外科门诊及住院患者,其中符合输尿管结石诊断标准以及中医辨证分型为湿热蕴结证型的患者74例。治疗组42例(56.8%),予体外冲击波碎石术联合服用自拟排石颗粒治疗。对照组32例(43.2%),予单纯体外冲击波碎石治疗。两组患者同时予相应的西医解痉止痛治疗。分析两组病例治疗总有效率及治愈率、主要临床症状及体征评分、输尿管结石排出时间、血尿等疗效指标变化,得出相应结论。结果:1、治疗组的治愈率为73.81%,总有效率为95.24%,对照组的治愈率为53.13%,总有效率为81.25%,两组相比P0.05有显著差异,表明对于治愈率、总有效率,治疗组疗效优于对照组。2、治疗组结石排出率(73.81%),与对照组(53.13%)相比较P0.05有显著差异,表明对于结石排出率,治疗组高于对照组。3、治疗组结石排出时间(8.87士2.23)天,与对照组(11.71士1.31)天相比P0.05有显著差异,表明对于结石排出时间,治疗组短于对照组。4、治疗组及对照组治疗前后主要临床症状体征评分(P0.05)有显著差异,表明上述两种治疗方案均明显缓解输尿管结石的症状及体征,治疗组疗效优于对照组。5、两组治疗后血尿(镜下血尿),治疗组为(4.33±2.51)个/HP,与对照组(5.44±1.88)个/HP相比,P0.05有差异,表明对于改善血尿症状,治疗组优于对照组。结论:遵循中医辨证施治指导原则,辽宁省中医院泌尿外科自拟清热利湿,通淋排石之排石颗粒,对输尿管结石经体外冲击波碎石术后的患者,有明显的促进结石排出作用。根据对比两组病例的主要临床疗效指标结果,研究表明治疗组比对照组能明显改善输尿管结石患者临床症状,提高结石排出率,减少结石排出时间,有较高临床应用价值。
[Abstract]:Objective: to observe the clinical effect of self-made lithotripsy combined with extracorporeal shock wave lithotripsy in the treatment of ureteral calculi with damp-heat accumulation, and to explore the cure rate of ureteral calculi after extracorporeal shock wave lithotripsy (ESWL). The effect of total efficiency, etc. Materials and methods: retrospective analysis was used to select outpatients and inpatients from January 2015 to January 2016 in the Urology Department of Liaoning Province traditional Chinese Medicine Hospital. 74 cases of ureterolithiasis were diagnosed according to the criteria of ureterolithiasis and syndrome differentiation of traditional Chinese medicine. 42 cases (56.8%) in the treatment group were treated with extracorporeal shock wave lithotripsy combined with self-made Paishi granule. 32 cases (43.2%) in the control group were treated with extracorporeal shock wave lithotripsy alone. The patients in both groups were treated with western medicine to relieve spasmolysis and pain at the same time. The total effective rate and cure rate, main clinical symptoms and signs, ureteral stone excretion time and hematuria were analyzed in the two groups, and the corresponding conclusions were drawn. Results: 1, the cure rate of the treatment group was 73.81, the total effective rate was 95.24, the cure rate of the control group was 53.133.13and the total effective rate was 81.250.There was significant difference between the two groups (P0.05), which indicated that the total effective rate was the cure rate. The curative effect of the treatment group was better than that of the control group. 2. The stone excretion rate in the treatment group (73.81%) was significantly higher than that in the control group (53.13%), which indicated that the stone excretion rate in the treatment group was higher than that in the control group. Compared with the control group (11.71 卤1.31) days, the stone excretion time of the treatment group (8.87 卤2.23) days was significantly different from that of the control group (11.71 卤1.31) days, which indicated that the stone excretion time of the treatment group was shorter than that of the control group. The scores of major clinical symptoms and signs before and after treatment were significantly different between the treatment group and the control group (P0.05), which indicated that the above two treatment schemes significantly alleviated the symptoms and signs of ureteral calculi, and the curative effect of the treatment group was better than that of the control group (5. 5%). Compared with the control group (5.44 卤1.88) / HP, the treatment group (4.33 卤2.51) / HP, was significantly higher than the control group (P0.05), which indicated that the treatment group was superior to the control group in improving hematuria symptoms. Conclusion: according to the guiding principle of syndrome differentiation and treatment of traditional Chinese medicine, the Chinese medicine department of traditional Chinese medicine of Liaoning province has the function of promoting the excretion of the ureteral stone by removing heat and dampness and removing the stone through the treatment of ureteral calculi after extracorporeal shock wave lithotripsy (ESWL). According to the results of the main clinical efficacy indexes of the two groups, the study shows that the treatment group can obviously improve the clinical symptoms of ureteral calculi patients, increase the stone excretion rate, reduce the stone excretion time, and has higher clinical application value than the control group.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R269

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