从炎性反应角度探讨清热解毒法治疗心力衰竭的意义
发布时间：2018-11-10 09:34
【摘要】：心力衰竭是各种心脏疾病发展的终末阶段,是导致心脏病患者病死的重要原因。近年来研究发现,炎性细胞因子在心力衰竭发生和进展过程中起到重要作用。文章结合中医毒邪致病理论和现代医学对炎性反应的认识,从病因病机、证候特征等角度分析了中医"热毒"理论与西医炎性反应学说的共同点,阐释了两者间的相关性,从新的视角对心力衰竭的病因病机进行了探讨。指出心力衰竭病机以气(阳)虚为本,血瘀毒热为标,内生毒热损心是其"标实"病机的重要方面,认为"清热解毒"在心力衰竭治疗中有重要意义。从理论、实验和临床等多维角度阐释"清热解毒"治疗心力衰竭的可行性,为其进一步的临床推广应用提供了客观依据。
[Abstract]:Heart failure is the terminal stage of the development of various heart diseases and an important cause of death in patients with heart disease. In recent years, inflammatory cytokines have been found to play an important role in the development and progression of heart failure. Based on the theory of pathogenic toxin of TCM and the understanding of inflammatory reaction in modern medicine, this paper analyzes the common ground between the theory of "heat toxin" of TCM and the theory of inflammatory reaction of western medicine from the angles of etiology, pathogenesis and syndrome characteristics, and explains the correlation between them. The etiology and pathogenesis of heart failure were discussed from a new perspective. It is pointed out that the pathogenesis of heart failure is based on deficiency of qi (yang), heat of blood stasis and toxin is the standard, and heat of endogenetic toxin is an important aspect of the pathogenesis of "standard reality". It is considered that "clearing heat and detoxifying" is of great significance in the treatment of heart failure. The feasibility of "clearing away heat and detoxification" in the treatment of heart failure is explained from the view of theory, experiment and clinic, which provides an objective basis for its further clinical application.
【作者单位】： 北京中医药大学;
【基金】：国家自然科学基金重点项目(No.81530100) 教育部新世纪优秀人才支持计划项目(No.NCET-13-0692) 北京中医药大学“杰出青年人才项目-优青”(No.2015-JYB-XYQ002)~~
【分类号】：R259
，
本文编号：2322064
[Abstract]:Heart failure is the terminal stage of the development of various heart diseases and an important cause of death in patients with heart disease. In recent years, inflammatory cytokines have been found to play an important role in the development and progression of heart failure. Based on the theory of pathogenic toxin of TCM and the understanding of inflammatory reaction in modern medicine, this paper analyzes the common ground between the theory of "heat toxin" of TCM and the theory of inflammatory reaction of western medicine from the angles of etiology, pathogenesis and syndrome characteristics, and explains the correlation between them. The etiology and pathogenesis of heart failure were discussed from a new perspective. It is pointed out that the pathogenesis of heart failure is based on deficiency of qi (yang), heat of blood stasis and toxin is the standard, and heat of endogenetic toxin is an important aspect of the pathogenesis of "standard reality". It is considered that "clearing heat and detoxifying" is of great significance in the treatment of heart failure. The feasibility of "clearing away heat and detoxification" in the treatment of heart failure is explained from the view of theory, experiment and clinic, which provides an objective basis for its further clinical application.
【作者单位】： 北京中医药大学;
【基金】：国家自然科学基金重点项目(No.81530100) 教育部新世纪优秀人才支持计划项目(No.NCET-13-0692) 北京中医药大学“杰出青年人才项目-优青”(No.2015-JYB-XYQ002)~~
【分类号】：R259
，
本文编号：2322064
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