耳穴贴压法联合五行音乐疗法干预中风后抑郁的临床研究
发布时间：2018-11-10 21:26
【摘要】：目的:研究耳穴贴压法联合五行音乐疗法治疗中风后抑郁(PSD)的临床疗效,观察其不良反应发生情况;同时通过对治疗前后血浆同型半胱氨酸(HCY)水平的比较,探讨作为炎症指标之一的HCY对PSD的影响。方法:将60例PSD患者,按照随机数字表法随机分为2组,治疗组采用耳穴贴压法联合五行音乐疗法治疗,对照组采用常规的氟西汀口服治疗,治疗疗程共4周。结果:(1)临床疗效评价:两组治疗后疗效均提高,治疗组有效率86.67%、对照组有效率83.33%,差异无统计学意义(P0.05)。(2)汉密尔顿抑郁量表-17项(HAMD-17项)评价:治疗组和对照组的HAMD-17项评分在治疗后较治疗前均有明显下降,各组组内比较差异显著,有统计学意义(P0.05),组间比较无统计学差异(P0.05)。(3)日常生活能力(ADL)评价:治疗组和对照组的ADL评分在治疗后较治疗前均有明显增加,各组组内比较差异显著,有统计学意义(P0.05),组间比较无统计学差异(P0.05)。(4)神经功能缺损评分量表(NIHSS)评价:治疗组和对照组的NHISS评分在治疗后较治疗前均有明显下降,各组组内比较差异显著,有统计学意义(P0.05),组间比较无统计学差异(P0.05)。(5)HCY值变化:治疗组和对照组的HCY值在治疗后较治疗前均有明显下降,各组组内比较差异显著,有统计学意义(P0.05),组间比较无统计学差异(P0.05)。(6)进行安全性分析,具有可行的安全性。治疗组不良反应发生率为13.33%,对照组不良反应发生率为30%,差异有统计学意义(P0.05)。结论:(1)耳穴贴压法联合五行音乐疗法能明显改善PSD患者的临床症状,提高患者生活质量,增加其康复的信心,无明显不良反应。该治疗方法疗效好,安全性高,具有进一步深入研究、开发应用的价值。(2)HCY水平的降低在一定程度上有益于PSD患者的康复。
[Abstract]:Objective: to study the clinical effect of auricular acupoint sticking and pressing combined with five elements music therapy in the treatment of post-apoplectic depression (PSD), and to observe the occurrence of adverse reactions. At the same time, by comparing plasma homocysteine (HCY) levels before and after treatment, the effect of HCY, one of the inflammatory markers, on PSD was discussed. Methods: sixty patients with PSD were randomly divided into two groups according to random number table. The treatment group was treated with auricular acupoint pressing combined with five elements music therapy and the control group was treated with routine oral fluoxetine for 4 weeks. Results: (1) Clinical efficacy evaluation: after treatment, the curative effect was improved in both groups, the effective rate in the treatment group was 86.67 and that in the control group was 83.33. There was no significant difference between the two groups (P0.05). (2)-17 items of Hamilton Depression scale (HAMD-17): the scores of HAMD-17 items in the treatment group and the control group were significantly lower than those before treatment, and the difference was significant in each group. There was statistical significance (P0.05). There was no significant difference between the groups (P0.05). (3). (ADL) evaluation of ADL: the ADL scores of the treatment group and the control group were significantly higher than that of the control group after treatment. The differences were significant in each group (P0.05). There was no significant difference between the two groups (P0.05). (4). The NHISS scores of the treatment group and the control group were significantly lower than those of the control group after treatment (P0.05). (4), and there was a significant difference in the NHISS score between the treatment group and the control group. There was statistical significance (P0.05), there was no significant difference between groups (P0.05). (5) HCY value change: the HCY value of treatment group and control group were significantly lower than before treatment, the difference was significant in each group. There was statistical significance (P0.05), there was no statistical difference between the groups (P0.05). (6), the safety analysis was feasible. The incidence of adverse reactions was 13.33 in the treatment group and 30 in the control group (P0.05). Conclusion: (1) Auricular point sticking and pressing combined with five elements music therapy can obviously improve the clinical symptoms, improve the quality of life of the patients with PSD, increase their confidence in rehabilitation, and have no obvious adverse reactions. This method has good curative effect and high safety, and has the value of further research and application. (2) the decrease of HCY level is beneficial to the rehabilitation of PSD patients to some extent.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R255.2
本文编号：2323650
[Abstract]:Objective: to study the clinical effect of auricular acupoint sticking and pressing combined with five elements music therapy in the treatment of post-apoplectic depression (PSD), and to observe the occurrence of adverse reactions. At the same time, by comparing plasma homocysteine (HCY) levels before and after treatment, the effect of HCY, one of the inflammatory markers, on PSD was discussed. Methods: sixty patients with PSD were randomly divided into two groups according to random number table. The treatment group was treated with auricular acupoint pressing combined with five elements music therapy and the control group was treated with routine oral fluoxetine for 4 weeks. Results: (1) Clinical efficacy evaluation: after treatment, the curative effect was improved in both groups, the effective rate in the treatment group was 86.67 and that in the control group was 83.33. There was no significant difference between the two groups (P0.05). (2)-17 items of Hamilton Depression scale (HAMD-17): the scores of HAMD-17 items in the treatment group and the control group were significantly lower than those before treatment, and the difference was significant in each group. There was statistical significance (P0.05). There was no significant difference between the groups (P0.05). (3). (ADL) evaluation of ADL: the ADL scores of the treatment group and the control group were significantly higher than that of the control group after treatment. The differences were significant in each group (P0.05). There was no significant difference between the two groups (P0.05). (4). The NHISS scores of the treatment group and the control group were significantly lower than those of the control group after treatment (P0.05). (4), and there was a significant difference in the NHISS score between the treatment group and the control group. There was statistical significance (P0.05), there was no significant difference between groups (P0.05). (5) HCY value change: the HCY value of treatment group and control group were significantly lower than before treatment, the difference was significant in each group. There was statistical significance (P0.05), there was no statistical difference between the groups (P0.05). (6), the safety analysis was feasible. The incidence of adverse reactions was 13.33 in the treatment group and 30 in the control group (P0.05). Conclusion: (1) Auricular point sticking and pressing combined with five elements music therapy can obviously improve the clinical symptoms, improve the quality of life of the patients with PSD, increase their confidence in rehabilitation, and have no obvious adverse reactions. This method has good curative effect and high safety, and has the value of further research and application. (2) the decrease of HCY level is beneficial to the rehabilitation of PSD patients to some extent.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R255.2
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