加味四参汤对缺血性心脏病室上性早搏患者心肌缺血总负荷的影响

发布时间：2018-11-23 12:54

【摘要】：目的：通过加味四参汤对缺血性心脏病室上性早搏治疗的观察,应用动态心电图,计算治疗前后心肌缺血总负荷、室上性早搏数的变化,探究其治疗效果。方法：将符合标准的患者62例随机分为对照组31例、治疗组31例,两组均进行冠心病基础治疗,治疗组加以口服加味四参汤治疗。两组治疗均为三周一疗程,观察、记录两组治疗前后的症状积分、心肌缺血总负荷、24小时动态心电早搏次数。结果：1、中医症状积分比较：两组治疗后较治疗前均降低,差异有统计学意义(P0.05),且治疗后治疗组比对照组降低明显,差异有统计学意义(P0.05)。2、心肌缺血总负荷比较：两组治疗后较治疗前相比均减少,差异有统计学意义(P0.05),且治疗后治疗组比对照组减少明显,差异有统计学意义(P0.05)。3、室上性早搏比较：治疗组总有效率为90.0%,高于对照组总有效率66.7%,差异有统计学意义(P0.05)。结论：1、加味四参汤在改善气阴两虚兼血瘀型缺血性心脏病室上性早搏患者中医症状方面有疗效。2、加味四参汤能降低气阴两虚兼血瘀型缺血性心脏病室上性早搏患者心肌缺血总负荷。3、加味四参汤能提高气阴两虚兼血瘀型缺血性心脏病室上性早搏患者室上性早搏总有效率。
[Abstract]:Objective: to observe the treatment of supraventricular premature beats in ischemic heart disease with modified Si-Shen decoction and to calculate the changes of total myocardial ischemic load and the number of supraventricular premature beats before and after treatment with dynamic electrocardiogram (ECG). Methods: 62 patients were randomly divided into control group (n = 31) and treatment group (n = 31). The two groups were treated for three weeks and one course of treatment. The symptom scores, total myocardial ischemia load and 24 hour dynamic electrocardiogram premature beats were recorded before and after treatment in both groups. Results: 1. Comparison of TCM symptom scores: after treatment, the two groups were lower than before treatment, the difference was statistically significant (P0.05), and the treatment group was significantly lower than the control group, the difference was statistically significant (P0.05). Comparison of the total load of myocardial ischemia: the two groups after treatment compared with the treatment before treatment, the difference was statistically significant (P0.05), and the treatment group after treatment than the control group decreased significantly, the difference was statistically significant (P0.05). Comparison of supraventricular premature beats: the total effective rate of the treatment group was 90.0, which was higher than that of the control group (66.7%), the difference was statistically significant (P0.05). Conclusion: 1, modified Sishen decoction is effective in improving TCM symptoms in patients with ischemic heart disease with deficiency of Qi and Yin and blood stasis. Jiawei Sishen decoction can reduce the total myocardial ischemic load in patients with ischemic heart disease with deficiency of Qi and Yin and blood stasis. Jiawei Sishen decoction can improve the total effective rate of supraventricular premature beats in patients with ischemic heart disease with deficiency of qi and yin and blood stasis.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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