药油灸对慢性非细菌性前列腺炎患者前列腺液中锌含量和C反应蛋白的影响

发布时间：2018-11-24 11:59

【摘要】：目的:观察药油灸、单纯艾灸与常规西药治疗慢性非细菌性前列腺炎(chronic nonbacterial prostatitis,CNP)的临床疗效差异及部分作用机制。方法:将120例符合入选标准的患者随机分为药油灸组、灸法组和西药组,每组40例。药油灸组与灸法组穴取关元、中极、气海及双侧阴陵泉、三阴交、肾俞、命门、膀胱俞、次毼、秩边,灸法组行单纯艾灸,药油灸组用药油外搽施灸穴位后同灸法组艾灸,每次约30 min,每日1次,腹部、背部交替进行。西药组口服盐酸坦索罗辛胶囊,每次1粒,每日1次。3组均治疗30 d,观察各组治疗前后及治疗后1个月随访时美国国立卫生院制定的慢性前列腺炎症状积分指数(NIH-CPSI)评分及锌(Zinc,Zn)、C反应蛋白(C-reactive protein,CRP)含量及前列腺液中白细胞数量(white blood cells,WBC)、卵磷脂小体计数,并于治疗后评价临床疗效。结果:药油灸组治疗后总有效率为90.0%(36/40),明显高于灸法组的72.5%(29/40)和西药组的62.5%(25/40,均P0.05)。治疗后及随访时,各组NIH-CPSI评分均低于治疗前(均P0.05),且药油灸组低于灸法组与西药组(均P0.05);各组Zn含量均高于治疗前(均P0.05),且药油灸组高于灸法组与西药组(均P0.05),灸法组高于西药组(均P0.05);各组CRP含量均低于治疗前(均P0.05),且药油灸组低于灸法组与西药组(均P0.05),灸法组低于西药组(P0.05);各组WBC计数均低于治疗前(均P0.05),且药油灸组低于灸法组与西药组(均P0.05);各组卵磷脂小体计数均高于治疗前(均P0.05),且药油灸组高于灸法组与西药组(均P0.05)。上述指标治疗前后组间差值比较,药油灸组均优于灸法组和西药组(均P0.05),其中Zn含量灸法组优于西药组(P0.05)。结论:药油灸治疗CNP临床疗效优于单纯艾灸与西药,在改善患者临床症状,升高Zn含量、卵磷脂小体计数,降低CRP含量、WBC计数方面具有优势。
[Abstract]:Objective: to observe the difference of clinical efficacy and mechanism of herbal moxibustion, simple moxibustion and conventional western medicine in the treatment of chronic nonbacterial prostatitis (chronic nonbacterial prostatitis,CNP). Methods: 120 patients were randomly divided into three groups: moxibustion group, moxibustion group and western medicine group. The moxibustion group and moxibustion group received moxibustion on the points of Guan Yuan, middle pole, air sea and bilateral Yin Ling Quan, Sanyinjiao, Shenshu, Shengmen, Biaoshu, Suzhuo, Rank side, moxibustion group, and moxibustion group were treated with moxibustion after applying moxibustion oil outside the acupoint, the moxibustion group was moxibustion with the same moxibustion method after applying moxibustion oil. Each time about 30 min, daily, abdomen, back alternately. The western medicine group was treated with tansoloxine hydrochloride capsule once a day for 30 days. To observe the scores of chronic prostatitis symptom score (NIH-CPSI) and Zinc,Zn), C reactive protein (C-reactive protein,) developed by the National Institutes of Health before and after treatment and 1 month after treatment. The content of CRP, the number of leukocytes in prostatic fluid (white blood cells,WBC), the count of lecithin corpuscles, and the clinical effect were evaluated after treatment. Results: the total effective rate of moxibustion group was 90.0% (36 / 40), which was significantly higher than that of moxibustion group (72.5%) and western medicine group (62.5%) (P 0.05). After treatment and follow-up, the scores of NIH-CPSI in each group were lower than those before treatment (P0.05), and those in moxibustion group were lower than those in moxibustion group and western medicine group (P0.05). The content of Zn in each group was higher than that before treatment (P0.05), and the content of Zn in moxibustion group was higher than that in moxibustion group and western medicine group (P0.05), and that in moxibustion group was higher than that in western medicine group (P0.05). The content of CRP in each group was lower than that before treatment (P0.05), and the content of CRP in moxibustion group was lower than that in moxibustion group and western medicine group (P0.05), and that in moxibustion group was lower than that in western medicine group (P0.05). The number of WBC in each group was lower than that before treatment (P0.05), and the number of WBC in moxibustion group was lower than that in moxibustion group and western medicine group (P0.05). The number of lecithin bodies in each group was higher than that before treatment (P0.05), and the number of lecithin bodies in moxibustion group was higher than that in moxibustion group and western medicine group (P0.05). The difference between the above indexes before and after treatment was better in moxibustion group than in moxibustion group and western medicine group (P0.05). The content of Zn in moxibustion group was better than that in western medicine group (P0.05). Conclusion: moxibustion with medicinal oil is superior to moxibustion and western medicine in the treatment of CNP. It has advantages in improving clinical symptoms, increasing Zn content, counting lecithin body, decreasing CRP content and WBC count.
【作者单位】：安徽中医药大学附属滁州市中西医结合医院泌尿男科;
【基金】：2014年度安徽省卫生计生委中医药科技课题:2014zy60
【分类号】：R246.9

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