针灸结合中药治疗退变性下颈椎不稳临床疗效及对血管活性因子的影响

发布时间：2018-12-12 09:48

【摘要】：目的:探讨针灸结合中药治疗退变性下颈椎不稳患者临床疗效及对血管活性因子的影响,为临床研究提供参考依据。方法:选择2013年1月—2015年12月120例退变性下颈椎不稳患者作为研究对象,采用随机数字表法分为观察组与对照组各60例,分别给予针灸结合中药治疗与单独针灸治疗,所有患者均治疗30 d,比较两组疗效,并抽取空腹血检测治疗前后血管活性因子一氧化氮(NO)及内皮素(ET)水平变化。结果:观察组总有效率95.0%明显高于对照组83.3%,差异有统计学意义(P0.05)。治疗后两组临床症状构成比均明显降低,差异有统计学意义(P0.05);观察组降低更明显(P0.05)。观察组治疗后ET为(64.52±12.47)ng/L,NO为(38.54±9.99)μmmol/L,与治疗前比较ET(88.89±12.92)ng/L,NO(62.64±10.11)μmmol/L,差异有统计学意义(P0.05)。对照组治疗后ET为(73.44±12.25)ng/L,NO为(47.84±10.12)μmmol/L,明显低于治疗前(88.90±14.21)ng/L,(62.41±9.72)μmmol/L,差异有统计学意义(P0.05)。且治疗后观察组明显低于对照组,差异有统计学意义(P0.05)。结论:针灸联合中药治疗退变性下颈椎不稳患者有更好的临床疗效,在有效改善患者症状的同可时以更明显降低血管活性因子。
[Abstract]:Objective: to explore the clinical effect of acupuncture and moxibustion combined with traditional Chinese medicine on degenerative cervical spine instability and its influence on vasoactive factors. Methods: from January 2013 to December 2015, 120 patients with degenerative lower cervical vertebra instability were divided into two groups: observation group (n = 60) and control group (n = 60). Acupuncture and moxibustion combined with traditional Chinese medicine and acupuncture alone were used respectively. All patients were treated for 30 days to compare the efficacy of the two groups. Fasting blood samples were taken to detect the changes of nitric oxide (NO) and endothelin (ET) levels before and after treatment. Results: the total effective rate in the observation group was 95.0% significantly higher than that in the control group (83.3%, P0.05). After treatment, the clinical symptom composition ratio of the two groups were significantly decreased, the difference was statistically significant (P0.05); the observation group decreased more significantly (P0.05). After treatment, the ET of the observation group was (64.52 卤12.47) ng/L,NO (38.54 卤9.99) 渭 mmol/L, which was significantly higher than that of the pre-treatment ET (88.89 卤12.92) ng/L,NO (62.64 卤10.11) 渭 mmol/L, (P0.05). The ET of the control group was (73.44 卤12.25) ng/L,NO (47.84 卤10.12) 渭 mmol/L, significantly lower than that of the pre-treatment (88.90 卤14.21) ng/L, (62.41 卤9.72) 渭 mmol/L, (P0.05). And the observation group after treatment was significantly lower than the control group, the difference was statistically significant (P0.05). Conclusion: acupuncture and moxibustion combined with traditional Chinese medicine are more effective in treating degenerative lower cervical spine instability.
【作者单位】：贵州医科大学附属医院中医科;
【基金】：国家中医药管理局名老中医传承工作室建设项目(2014)
【分类号】：R274.9

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