中医疗法预防脑卒中后抑郁有效性的系统评价

发布时间：2018-12-13 22:09

【摘要】：目的系统评价中医疗法预防脑卒中后抑郁(PSD)的有效性。方法 2名研究员以"针刺""针灸""中药""预防""脑卒中""中风""Chinese herb""acupuncture""prevention""post stroke depression"为主题词系统检索中国知网(CNKI)数据库、VIP数据库、万方数据库、Pub Med、MEDLINE 5个数据库的较高质量随机对照试验(RCT)、半随机对照试验(CCT)文献,经严格筛选、排除后,对符合要求的文献利用Rev Man5.3软件进行系统评价。结果共纳入8篇符合要求的文献,1065例患者,Meta分析结果显示,中医疗法与对照组相比较,能有效预防脑卒中后抑郁症的发生,OR=0.38,95%CI[0.28,0.51](P0.00001)。结论中医疗法能有效预防PSD的发生,但是由于研究样本量较少,仍需更多优质文献予以验证。
[Abstract]:Objective to evaluate the effectiveness of traditional Chinese medicine (TCM) therapy in the prevention of post-stroke depression (PSD). Methods two researchers used "acupuncture", "acupuncture," traditional Chinese medicine, "prevention of stroke," Chinese herb, "acupuncture," prevention, "post stroke depression" as the subject words to systematically search the (CNKI) database and VIP database in China. The literature of (RCT), semi-randomized controlled trial (CCT) with high quality in Wanfang database and 5 databases of Pub Med,MEDLINE was selected strictly and excluded, and the literature that met the requirements was evaluated by Rev Man5.3 software. Results A total of 8 articles were included, 1065 patients were included. Meta analysis showed that TCM therapy could effectively prevent depression after stroke compared with the control group, OR=0.38,95%CI [0.280.51] (P0.00001). Conclusion TCM therapy can effectively prevent the occurrence of PSD, but because of the small amount of research samples, it still needs more high-quality literature to verify.
【作者单位】：天津中医药大学;天津中医药大学第一附属医院;
【基金】：国家中医药管理局中医药行业科研专项(201407001-6B)
【分类号】：R277.7

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