中医药治疗动脉粥样硬化新进展
发布时间：2018-12-15 20:23
【摘要】：现代医学对动脉粥样硬化(AS)发病机制的深入探索,不断启发着中医药对AS病因病机的认识。目前研究认为,AS是由多种原因导致的复杂疾病,其发病不单纯是由于"痰、瘀、毒"三因素,脾肾亏虚,营卫失调,肺失治节亦是导致AS的重要原因,因此,选用单一作用靶点药物很难取得满意疗效。而中医药具有多重作用机制,为有效治疗AS提供了可能。近年来临床采用具有补肾、活血、化痰、益气、化积等功效的方药防治AS取得了较好疗效;基础实验从细胞自噬、内质网应激、细胞凋亡等新视角初步阐释了中医药治疗AS的科学内涵。
[Abstract]:The further exploration of the pathogenesis of atherosclerosis (AS) in modern medicine has inspired the understanding of the etiology and pathogenesis of AS. At present, it is believed that AS is a complex disease caused by many causes, and its pathogenesis is not simply caused by "phlegm, blood stasis, toxin", deficiency of spleen and kidney, imbalance of Ying Wei, and loss of lung treatment are also important causes of AS. It is difficult to obtain satisfactory curative effect by using single target drug. Traditional Chinese medicine (TCM) has multiple mechanisms, which provides a possibility for the effective treatment of AS. In recent years, the clinical use of tonifying kidney, promoting blood circulation, resolving phlegm, benefiting qi, removing accumulation and other efficacy of prescription to prevent and cure AS has obtained good curative effect. The scientific connotation of traditional Chinese medicine (TCM) in the treatment of AS was preliminarily explained from the perspectives of autophagy, endoplasmic reticulum stress and apoptosis.
【作者单位】： 天津中医药大学第一附属医院;天津中医药大学;
【基金】：国家自然科学基金青年基金项目(No.81403334)~~
【分类号】：R259
本文编号：2381233
[Abstract]:The further exploration of the pathogenesis of atherosclerosis (AS) in modern medicine has inspired the understanding of the etiology and pathogenesis of AS. At present, it is believed that AS is a complex disease caused by many causes, and its pathogenesis is not simply caused by "phlegm, blood stasis, toxin", deficiency of spleen and kidney, imbalance of Ying Wei, and loss of lung treatment are also important causes of AS. It is difficult to obtain satisfactory curative effect by using single target drug. Traditional Chinese medicine (TCM) has multiple mechanisms, which provides a possibility for the effective treatment of AS. In recent years, the clinical use of tonifying kidney, promoting blood circulation, resolving phlegm, benefiting qi, removing accumulation and other efficacy of prescription to prevent and cure AS has obtained good curative effect. The scientific connotation of traditional Chinese medicine (TCM) in the treatment of AS was preliminarily explained from the perspectives of autophagy, endoplasmic reticulum stress and apoptosis.
【作者单位】： 天津中医药大学第一附属医院;天津中医药大学;
【基金】：国家自然科学基金青年基金项目(No.81403334)~~
【分类号】：R259
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