基于数据挖掘方法对李丽芸辨治不孕症的临床用药规律研究

发布时间：2018-12-18 16:53

【摘要】：目的:分析李丽芸教授辨治女性不孕症的用药规律,总结其对本病的临床辨证论治思路。方法:通过文献检索、方药检索、专家阐释、类方查找、专家认证过程,对其临床验方进行方理及类方比较研究,应用频数统计、Apriori算法等数据挖掘方法对其治疗的137例不孕症病例数据进行关联分析。结果:在对742张处方统计分析中发现,使用频率最高的方为8、3、1方,补血药、补阳药、活血化瘀药物使用频率最高10%,30~40岁患者常用25、19、2方,排卵障碍患者常用19、16、26方,月经期擅用10方,卵泡期擅用3方,黄体期擅用8方,并挖掘出8个常用药对。结论:李丽芸教授辨治不孕症重视肾与命门,次及脾胃,以肝为先天之思路,善用分期、分时结合治疗模式辨治。
[Abstract]:Objective: to analyze the rule of treatment of female infertility by Professor Li Liyun, and to summarize the clinical thinking of syndrome differentiation and treatment of this disease. Methods: through literature retrieval, prescription search, expert interpretation, class search, expert certification process, the clinical prescriptions were compared with each other, and the frequency statistics were used. Data mining methods such as Apriori algorithm were used to analyze the data of 137 infertility cases. Results: in the statistical analysis of 742 prescriptions, it was found that the most frequently used prescriptions were 8fen 3DU 1, blood tonifying drugs, Yang tonifying drugs, promoting blood circulation and removing blood stasis drugs were used frequently in patients aged 30 to 40 years old. Ten sides of menstrual period, 3 sides of follicular phase and 8 sides of luteal phase were excavated. Conclusion: professor Li Liyun pays more attention to the kidney, the life gate, the times and the spleen and stomach, takes the liver as the innate train of thought, makes good use of the stages, and combines the treatment model with time sharing.
【作者单位】：广州中医药大学第二临床医学院;广州中医药大学博士后科研流动站;
【基金】：国家中医药管理局课题(1199ws02)-李丽芸全国名老中医药专家传承工作室广东省科学技术厅—广东省中医药科学院联合科研专项(2012A032500007)-基于方证信息采集探索李丽芸教授辨治不孕症的经验挖掘研究
【分类号】：R249;R271.14

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