缪希雍降气法治疗功能性便秘肠道气滞证的临床研究

发布时间：2019-01-05 17:49

【摘要】：目的：运用缪希雍降气法,使用苏子、枇杷叶降气,联合自拟润肠通便方治疗功能性便秘,通过与单纯运用自拟润肠通便方治疗功能性便秘疗效的对比,观察前法在改善便秘症状、缓解患者精神心理状况等方面是否具有优势。丰富功能性便秘的治疗方法,研究并拓展缪希雍学术思想。方法：采用临床研究方法,选择符合纳入标准的功能性便秘患者57例,随机分为两组,治疗组29例和对照组28例。对照组服用自拟润肠通便方,治疗组在对照组方药基础上加用苏子10g,枇杷叶lOg。两组均服用1个疗程,共4周时间。比较两组患者的便秘症状评分、综合疗效评定及焦虑(SAS)、抑郁(SDS)自评量表评分。结果：两组在治疗后便秘症状积分较前均降低(P0.05),且治疗组P0.01,差异具有显著统计学意义。治疗后两组之间的症状积分差异具有统计学意义(P=0.040.05)。综合疗效评定方面,治疗组总有效率86.2%,而对照组总有效率60.7%,治疗组优于对照组,差异有统计学意义(P0.05)。在改善患者焦虑、抑郁状况方面,与本组治疗前相比,对照组改善不明显,差异无统计学意义(P0.05)；治疗组改善较明显,差异有统计学意义(P0.05),且与对照组治疗后相比,差异有统计学意义(P0.05)。结论：使用缪希雍降气法治疗功能性便秘,在自拟润肠通便汤原方基础上加入苏子、枇杷叶两味降气药,对于在改善患者便秘症状及精神心理状况等方面均具有较好疗效。
[Abstract]:Objective: to treat functional constipation with Miuxiyong Jiangqi method, Su Zi, loquat leaf and self-made Runchang Tongbian recipe, and to compare the curative effect of using self-made Runchang Tongbian recipe to treat functional constipation. Whether the pre-observation method has advantages in improving constipation symptoms and relieving psycho-psychological status of patients. Enrich the treatment of functional constipation, research and expand the academic thinking of Mixion. Methods: a total of 57 patients with functional constipation were randomly divided into two groups: treatment group (n = 29) and control group (n = 28). The control group took the self-made Runchang Tongbian recipe, and the treatment group was treated with 10 g of perilla seed and lOg. of loquat leaf on the basis of the prescription of the control group. Both groups were given a course of treatment for 4 weeks. The scores of constipation symptom, comprehensive curative effect and anxiety (SAS), depression (SDS) scale were compared between the two groups. Results: the scores of constipation symptoms in the two groups were lower than those before treatment (P0.05), and the difference was statistically significant in the treatment group (P0.01). There was significant difference in symptom score between the two groups after treatment (P < 0.040.05). The total effective rate of the treatment group was 86.2 and the total effective rate of the control group was 60.7. The treatment group was better than the control group, the difference was statistically significant (P0.05). In improving the anxiety and depression of patients, compared with this group before treatment, the control group did not improve significantly, the difference was not statistically significant (P0.05). Treatment group improved significantly, the difference was statistically significant (P0.05), and compared with the control group after treatment, the difference was statistically significant (P0.05). Conclusion: using Miuxiyong Jiangqi method to treat functional constipation, adding Su Zi on the basis of self-made Runchang Tongbian decoction, loquat leaf two kinds of qi reducing medicine, has better curative effect on improving constipation symptom and mental and psychological condition of patients.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R256.35

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