连礞汤灌肠治疗痰瘀交阻型室性早搏的临床观察

发布时间：2019-01-26 13:07

【摘要】：目的:在中医理论的指导下,观察全国名老中医郭文勤教授自拟方连礞汤灌肠治疗痰瘀交阻型室性早搏(PVCs)的临床疗效及安全性,通过相关指标的剖析,探讨连礞汤灌肠法在中医临床上的可行性及使用价值。方法:将符合标准的黑龙江省中医药科学院南岗分院心二科痰瘀交阻型室性早搏患者60例,随机分为二组,二组之间年龄、病程长短、性别等无显著差异,其中美西律口服组30例,连礞汤灌肠组30例。连礞汤灌肠组给予连礞汤保留灌肠治疗,美西律口服组予单纯美西律治疗,三个星期为一疗程,观察一疗程。分别观察二组治疗后的临床症状、中医症状积分、24H动态心电图室早次数和疗效变化情况。结果:1.在改善中医临床症状方面,两组治疗后均能改善患者中医临床症状,连礞汤灌肠组与美西律口服组比较有显著差异(p0.05),连礞汤灌肠组优于美西律口服组;2.在室性早搏疗效方面,二组治疗后均能减少室性早搏的发生次数,连礞汤灌肠组与美西律口服组比较无显著差异(p0.05),连礞汤灌肠组疗效近似于美西律口服组。结论:1.连礞汤灌肠治疗痰瘀交阻型室性早搏疗效显著,能改善患者临床症状,提高患者的生活质量。2.连礞汤灌肠治疗痰瘀交阻型室性早搏,能明显减少室性早搏发生频率。
[Abstract]:Objective: to observe the clinical efficacy and safety of Professor Guo Wenqin, a famous Chinese medicine professor, in the treatment of phlegm and blood stasis type ventricular premature beat (PVCs) by using Chinese medicine theory. To explore the feasibility and application value of LianMengtang enema in TCM. Methods: sixty patients with ventricular premature beats of phlegm and blood stasis type were randomly divided into two groups. There was no significant difference between the two groups in age, duration of disease, sex and so on. There were 30 cases in mesiglitazone oral group and 30 cases in LianMengtang enema group. LianMengtang enema group was treated by retention enema with LianMengtang, and mesiglitazol oral group was treated by mesiglitazol alone, three weeks as a course of treatment, and a course of treatment was observed. The clinical symptoms, TCM symptom score, 24 H ambulatory electrocardiogram (24 H) ventricular premature rate and curative effect were observed in the two groups. Results: 1. In improving the clinical symptoms of traditional Chinese medicine, the two groups can improve the clinical symptoms of Chinese medicine after treatment, LianMengtang enema group and mesiglitazol oral group have significant difference (p0.05), LianMengtang enema group is better than methyclol oral group; 2. In terms of the effect of ventricular premature beat, both groups could reduce the frequency of ventricular premature beat after treatment. There was no significant difference between LianMengtang enema group and mexilol oral group (p0.05), and the curative effect of LianMengtang enema group was similar to that of mesiglitazol oral group. Conclusion: 1. Mengtang enema treatment of phlegm and blood stasis obstruction of ventricular premature beats has a significant effect, can improve the clinical symptoms of patients, improve the quality of life of patients. 2. Mengtang enema can reduce the frequency of ventricular premature beats.
【学位授予单位】：黑龙江省中医药科学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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