同仁堂舒肝丸联合防风通圣丸治疗围绝经期抑郁肥胖临床观察

发布时间：2019-03-15 11:39

【摘要】：目的:探讨同仁堂舒肝丸与防风通圣丸联合方案在围绝经期抑郁肥胖治疗中的临床应用效果。方法:选择2014年1月-2016年1月北京同仁堂中医医院收治的围绝经期抑郁并肥胖患者作为研究对象,共计70例。根据随机数表法将70例患者平均分为两组,即研究组与对照组,各35例。对照组应用安慰剂、氟西汀及针灸治疗,研究组在对照组的基础上应用同仁堂舒肝丸联合防风通圣丸治疗。结果:研究组治疗的总有效率为88.57%,对照组为62.86%,研究组总有效率高于对照组(P0.05)。两组治疗前BMI指数、体质量及HAMD评分对比差异无统计学意义;治疗后两组患者BMI指数、体质量及HAMD评分较治疗前均显著降低,研究组治疗后BMI指数、体质量及HAMD评分均低于对照组(P0.05)。两组治疗前FSH与E2水平对比差异无统计学意义;治疗后两组患者FSH低于治疗前、E2高于治疗前(P0.05),且研究组治疗后FSH水平低于对照组(P0.05),E2水平高于对照组(P0.05)。结论:同仁堂舒肝丸联合防风通圣丸治疗围绝经期抑郁肥胖效果显著,可以有效调节体质量,改善不良心理状况,适于临床应用。
[Abstract]:Objective: to investigate the clinical effect of Tongren Tang Shugan Pill and Fangfeng Tongsheng Pill in the treatment of perimenopause depression and obesity. Methods: 70 patients with perimenopause depression and obesity were selected from January 2014 to January 2016 in Tongrentang traditional Chinese Medicine Hospital. According to the randomized table method, 70 patients were divided into two groups: study group (n = 35) and control group (n = 35). The control group was treated with placebo, fluoxetine and acupuncture. The study group was treated with Tongren Tang Shugan Pill combined with Fangfeng Tongsheng Pill on the basis of the control group. Results: the total effective rate was 88.57% in the study group and 62.86% in the control group. The total effective rate in the study group was higher than that in the control group (P0.05). There was no significant difference in BMI index, body mass and HAMD score between the two groups before treatment. After treatment, the BMI index, body mass and HAMD score in the two groups were significantly lower than those before treatment. The BMI index, body mass and HAMD score in the study group after treatment were lower than those in the control group (P0.05). There was no significant difference in the levels of FSH and E2 between the two groups before treatment. After treatment, the level of FSH in the two groups was lower than that before treatment, and the level of E2 in the study group was lower than that in the control group after treatment (P0.05), and the level of E2 in the study group was higher than that in the control group (P0.05). Conclusion: Tongren Tang Shugan Pill combined with Fangfeng Tongsheng Pill is effective in the treatment of perimenopause depression and obesity, which can effectively regulate body mass and improve bad psychological condition, so it is suitable for clinical application.
【作者单位】：北京同仁堂中医医院中医内科;北京安定医院抑郁症治疗中心;
【基金】：北京市中医药薪火传承“3+3”工程项目(No.2012-SZ-B-27) 国家中医药管理局全国名老中医药专家传承工作室建设项目~~
【分类号】：R259

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