补肾法防治经间期出血的临床观察

发布时间：2019-04-26 13:51

【摘要】：目的：通过收集经间期出血患者的临床资料,对纳入患者运用补肾法进行防治并对其症状改善情况进行临床观察,同时评价补肾法防治经间期出血的临床疗效,旨在为临床治疗经间期出血提供一种防治结合的有效治疗方法。方法：本组入选病例62例,对患者的一般资料进行采集,根据患者的出血期、非出血期及生育要求等状况给予患者相应的补肾中药汤剂口服,服药时间超过以往的出血时间,连续治疗3个月经周期后,观察患者的综合疗效、止血情况、主症及次症积分变化。将患者的一般资料及治疗前后的相关数据录入SPSS19.0并运用该软件进行统计分析。通过中医症候积分变化评价补肾法的临床疗效,通过查阅文献进一步了解补肾法防治经间期出血的作用机理。结果：1.综合疗效：本组62例患者中,痊愈21例,显效26例,有效10例,无效5例,总有效率达91.94%。2.止血效果：本组62例患者中,痊愈37例,显效13例,有效7例,无效5例,总有效率达91.94%。3.中医症候积分：治疗前后的中医症候总积分经秩和检验Z=-6.57,P=0.000.05,治疗前后的主症积分经秩和检验Z=-7.42,P=0.000.05,差异均有统计学意义,结果表明治疗后中医症候总积分及主症积分均有明显下降。4.相关因素与疗效：年龄、病程、职业、孕产次、BMI均对疗效无明显影响,不同肾虚证型的患者疗效亦基本相当。然而,病情程度对疗效有一定影响。结论：1.补肾法防治肾阳虚、肾阴虚、肾气虚型经间期出血可使中医症候评分明显降低,综合疗效及止血疗效确切,对于该病主症及各证型次症的改善效果显著。近期及远期疗效确切,值得临床推广应用。2.对于相关因素与疗效的统计分析表明,年龄、病程、职业、孕产次、BMI均对疗效无明显影响,不同肾虚证型的患者疗效亦基本相当。然而,病情程度对疗效有一定影响。
[Abstract]:Objective: to collect the clinical data of patients with intermenstrual hemorrhage and to evaluate the clinical efficacy of tonifying kidney method in the prevention and treatment of intermenstrual hemorrhage by using the method of tonifying kidney and improving its symptoms, and to evaluate the clinical efficacy of tonifying kidney method in the prevention and treatment of intermenstrual hemorrhage. The aim of this study is to provide an effective method for the treatment of intermenstrual hemorrhage. Methods: 62 cases were selected and the general data of the patients were collected. According to the patient's bleeding period, non-hemorrhagic period and fertility requirement, the patients were given the corresponding tonifying kidney Chinese medicine decoction orally, the time of taking medicine was longer than the previous bleeding time, and the time of taking medicine was longer than the previous bleeding time. After 3 months of continuous treatment, the comprehensive curative effect, hemostasis, integral changes of main and secondary symptoms were observed. The general data of the patients and the related data before and after treatment were entered into SPSS19.0 and the software was used for statistical analysis. The clinical curative effect of tonifying kidney method was evaluated by the change of TCM syndrome integral, and the mechanism of tonifying kidney method to prevent and treat intermenstrual hemorrhage was further understood by consulting the literature. Results: 1. Comprehensive curative effect: 21 cases were cured, 26 cases were markedly effective, 10 cases were effective and 5 cases were ineffective. The total effective rate was 91.94%. Hemostatic effect: 37 cases were cured, 13 cases were markedly effective, 7 cases were effective and 5 cases were ineffective. The total effective rate was 91.94%. TCM symptom score: before and after treatment, the total score of TCM syndrome was tested by rank sum test (Z) 6.57, P < 0.005, and the scores of main symptoms before and after treatment were tested by rank sum test (7.42), P < 0.0005 (P < 0.05), the difference was statistically significant. The results showed that the total scores of TCM symptoms and the scores of main symptoms decreased significantly after treatment. 4. Related factors and curative effect: age, course of disease, occupation, pregnancy and childbirth, BMI had no obvious effect on the curative effect, and the curative effect of different types of kidney deficiency syndrome was basically the same as that of the patients with different types of kidney deficiency syndrome. However, the severity of the disease has a certain effect on the curative effect. Conclusion: 1. The method of tonifying the kidney to prevent and treat kidney yang deficiency, kidney yin deficiency, kidney qi deficiency type of intermenstrual hemorrhage can obviously reduce the syndrome score of traditional Chinese medicine, the comprehensive curative effect and hemostatic effect are definite, and the improvement effect is remarkable for the main disease and the secondary syndrome of each syndrome type. The short-term and long-term curative effect is definite, which is worthy of clinical application. 2. The statistical analysis of related factors and curative effect showed that age, course of disease, occupation, pregnancy and childbirth, and BMI had no significant effect on the curative effect, and the curative effect of patients with different types of kidney deficiency syndrome was basically the same as that of the patients with different types of kidney deficiency syndrome. However, the severity of the disease has a certain effect on the curative effect.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.11

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