益气活血方治疗小儿过敏性紫癜临床疗效观察

发布时间：2019-05-18 21:48

【摘要】：目的:观察自拟的益气活血方治疗小儿反复发作性过敏性紫癜(皮肤型)的临床疗效,初步探讨其作用机理,为临床治疗提供参考依据。方法:将纳入该研究的37例患儿资料记入自行设计的调查表,整理所得数据,运用SPSS统计软件,对其临床疗效、症状改善积分及随访结果等进行统计分析,并探讨其疗效机理。结果:益气活血方治疗儿童反复发作性过敏性紫癜(皮肤型),总有效率94.59%;治疗前后症状平均积分比较有统计学差异(P0.05),治疗前后症状体征总积分、紫癜分布积分、紫癜持续时间积分、紫癜反复次数积分及一般情况积分等比较有统计学差异(P0.05);随访半年,35例临床治疗有效患儿均无继发肾脏损害,但2例出现紫癜复发。结论:益气活血方治疗小儿反复发作性过敏性紫癜(皮肤型)临床有效,能明显改善临床症状,特别是在改善紫癜分布、持续时间、反复次数等方面疗效显著,值得进一步研究和应用。
[Abstract]:Objective: to observe the clinical efficacy of Yiqi Huoxue recipe in the treatment of recurrent allergic purpura (skin type) in children, and to explore its mechanism, so as to provide reference for clinical treatment. Methods: the data of 37 children included in the study were recorded into the self-designed questionnaire, the data were sorted out, the clinical efficacy, symptom improvement score and follow-up results were statistically analyzed by using SPSS statistical software, and the mechanism of curative effect was discussed. Results: Yiqi Huoxue recipe was used to treat recurrent Henoch-Schonlein purpura (skin type) in children, and the total effective rate was 94.59%. There was significant difference in the average score of symptoms and signs before and after treatment (P 0.05). The total score of symptoms and signs, the distribution score of purpura and the score of duration of purpura were statistically different before and after treatment. The scores of repeated times and general conditions of purpura were statistically different (P 0.05). After half a year follow-up, 35 children with effective clinical treatment had no secondary renal damage, but 2 patients had recurrence of purpura. Conclusion: Yiqi Huoxue recipe is effective in the treatment of recurrent Henoch-Schonlein purpura (skin type) in children, and can obviously improve the clinical symptoms, especially in improving the distribution, duration and frequency of repeated purpura. It is worthy of further study and application.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R272

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