知柏地黄丸加减治疗肾阴虚型绝经综合征的临床观察

发布时间：2019-06-02 16:13

【摘要】：目的:随着生活水平的提高,从过去的求医问药,演变今日的养生保健,更多的女性将绝经综合征的治疗放在了首位,而中医治疗围绝经期综合征无论是从长远考虑还是药理的毒副作用都要好于西医治疗,作为医者更应将“为患者缓解身心伤害”作为根本,而此论文主要讨论知柏地黄丸加减治疗肾阴虚型绝经综合征实际服用意义,通过临床观察研究,探究知柏地黄丸的有效性及安全性。方法:拟定将72例符合入组标准的女性患者随机分为治疗组和对照组。使治疗组与对照组各36例,知柏地黄丸(免煎颗粒)给予治疗组,坤泰胶囊给予对照组。规定连续服用4周,自服药起28天后观察疗效。主要观察患者烘热汗出主症、兼症积分变化情况,统计临床疗效。结果:治疗组总有效率为88.89%,对照组总有效率为72.22%,通过试验研究,使用药物后治疗组与对照组临床效果明显,患者治疗后中医症候总积分比治疗前均显著下降(P0.05),同时使用药物后治疗组与对照组之间也具有显著的差异,组间差异明显(P0.05)。此次试验充分说明治疗组优于对照组。结论:运用中医药治疗绝经综合征方法多样、可靠,经过临床病例观察知柏地黄丸治疗肾阴虚型绝经综合征,其疗效明显,临床应用比较安全。
[Abstract]:Objective: with the improvement of living standards, from the past medical treatment to today's health care, more women put the treatment of menopausal syndrome in the first place. However, the toxic and side effects of traditional Chinese medicine in the treatment of menopausal syndrome are better than those of western medicine in terms of long-term consideration and pharmacological side effects. As doctors, they should take "relieving physical and mental injury for patients" as the foundation. This paper mainly discusses the practical significance of Zhibai Dihuang Pill in the treatment of kidney yin deficiency menopausal syndrome, and explores the effectiveness and safety of Zhibai Dihuang Pill through clinical observation and research. Methods: 72 female patients who met the admission criteria were randomly divided into treatment group and control group. 36 cases in the treatment group and 36 cases in the control group were treated with Zhibai Dihuang pill (no decoction granule) and Kuntai capsule in the control group. The curative effect was observed 28 days after taking the medicine for 4 weeks. The main symptoms of drying heat and sweating were observed, and the changes of concurrent score were observed, and the clinical curative effect was counted. Results: the total effective rate was 88.89% in the treatment group and 72.22% in the control group. Through the experimental study, the clinical effect of the treatment group and the control group was obvious. After treatment, the total score of TCM symptoms was significantly lower than that before treatment (P 0.05). At the same time, there was also significant difference between the treatment group and the control group after treatment, and there was significant difference between the two groups (P 0.05). This trial fully shows that the treatment group is superior to the control group. Conclusion: there are many and reliable methods in the treatment of menopausal syndrome with traditional Chinese medicine. Zhibai Dihuang Pill is effective and safe in the treatment of menopausal syndrome of kidney yin deficiency after clinical observation.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.116

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