幽门螺杆菌相关性消化性溃疡的证候分布规律探究
发布时间：2019-06-03 09:07
【摘要】：目的：初步探讨幽门螺杆菌相关性消化性溃疡的中医证候分布规律、HP与中医证候的相关性等,从而为中医药临床规范有效治疗本病提供一定临床依据。方法：选取符合标准的患者病例共200例,根据患者一般资料建立数据库,应用频数分析分析患者一般资料,系统聚类分析法归纳出中医证型,频数分析及卡方检验分析中医证型分布情况,结合专业知识分析幽门螺杆菌相关性消化性溃疡的证候分布情况,并初步探讨其证型分布规律。结果：本研究随机200例患者病例资料男性多于女性,青年组和中年组所占比例均等且较大、老年组较小；吸烟、饮洒、药物、饮食、情绪均为重要的发病因素；十二指肠溃疡多于胃溃疡,复合性溃疡最少；溃疡活动期摄多,愈合期次之,瘢痕期最少：200例患者中溃疡再发人数所占比例较大。系统聚类得出证候分布频数依次为：肝气犯胃证(29.5%)胃阴不足证(20.5%)脾胃虚寒证(19%)脾胃湿热证(12%)胃络瘀阻证(9.5%)和脾胃气虚证(9.5%)。各个证型年龄段的分布结果差异具有统计学意义(P=0.030.05)。结论：1.Hp相关性消化性溃疡患者以中年、男性多见；部位以十二指肠溃疡多见：分期以活动期多见；吸烟、饮酒、饮食、心理与情绪、阿司匹林等因素对溃疡的发病不可忽视。2.通过系统聚类方法总结出临床上6个中医证型,依照频数分布依次为肝气犯胃证、胃阴不足证、脾胃虚寒证、脾胃湿热证、胃络瘀阻证和脾胃气虚证。3.肝气犯胃证、脾胃湿热证主要见于青、中年患者,胃阴不足证、胃络瘀阻证多见于中、老年患者,脾胃虚寒证及脾胃气虚证反而青年患者多见；幽门螺杆菌相关性消化性溃疡患者男性各个证型均多于女性,且无论男女皆以肝气犯胃证多见。4.胃溃疡及十二指肠溃疡属肝气犯胃者最多,复合性溃疡证型属胃阴不足者最多,虽然溃疡部位不同但均可见各证型。5.消化性溃疡的复发与Hp感染密切相关,中医药在根除Hp、降低溃疡复发率、促进溃疡愈合质量(Quality of ulcer Healing, QOUH)等方面具有一定的优势。
[Abstract]:Objective: to investigate the distribution of TCM syndromes and the correlation between HP and TCM syndromes of HP-associated peptic ulcer, so as to provide some clinical basis for the effective treatment of HP-associated peptic ulcer. Methods: a total of 200 patients were selected to establish a database according to the general data of the patients. The general data of the patients were analyzed by frequency analysis, and the TCM syndrome types were summarized by systematic cluster analysis. Frequency analysis and chi-square test were used to analyze the distribution of TCM syndrome types, combined with professional knowledge, the syndrome distribution of HP-associated peptic ulcer was analyzed, and the distribution law of syndrome types was discussed. Results: the data of 200 patients in this study were more in males than in females. The proportion of young group and middle-aged group was equal and larger, but the elderly group was smaller. Smoking, drinking, medicine, diet and emotion were important factors. Duodenal ulcer was more than gastric ulcer, compound ulcer was the least, ulcer active stage was more, healing stage was the second, scar stage was the least: 200 cases of ulcer recurrence accounted for a large proportion. The distribution frequency of syndrome was as follows: liver qi invading stomach syndrome (29.5%), stomach yin deficiency syndrome (20.5%), spleen and stomach deficiency cold syndrome (19%), spleen and stomach dampness and heat syndrome (12%), gastric collateral stasis syndrome (9.5%) and spleen and stomach stasis syndrome (9.5%). Qi deficiency syndrome (9.5%). There was significant difference in the distribution results of each syndrome age group (P 鈮，
本文编号：2491825
[Abstract]:Objective: to investigate the distribution of TCM syndromes and the correlation between HP and TCM syndromes of HP-associated peptic ulcer, so as to provide some clinical basis for the effective treatment of HP-associated peptic ulcer. Methods: a total of 200 patients were selected to establish a database according to the general data of the patients. The general data of the patients were analyzed by frequency analysis, and the TCM syndrome types were summarized by systematic cluster analysis. Frequency analysis and chi-square test were used to analyze the distribution of TCM syndrome types, combined with professional knowledge, the syndrome distribution of HP-associated peptic ulcer was analyzed, and the distribution law of syndrome types was discussed. Results: the data of 200 patients in this study were more in males than in females. The proportion of young group and middle-aged group was equal and larger, but the elderly group was smaller. Smoking, drinking, medicine, diet and emotion were important factors. Duodenal ulcer was more than gastric ulcer, compound ulcer was the least, ulcer active stage was more, healing stage was the second, scar stage was the least: 200 cases of ulcer recurrence accounted for a large proportion. The distribution frequency of syndrome was as follows: liver qi invading stomach syndrome (29.5%), stomach yin deficiency syndrome (20.5%), spleen and stomach deficiency cold syndrome (19%), spleen and stomach dampness and heat syndrome (12%), gastric collateral stasis syndrome (9.5%) and spleen and stomach stasis syndrome (9.5%). Qi deficiency syndrome (9.5%). There was significant difference in the distribution results of each syndrome age group (P 鈮，
本文编号：2491825
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