克敏颗粒治疗儿童湿疹（脾虚食湿蕴积证）临床疗效观察

发布时间：2019-06-06 11:08

【摘要】：目的:观察克敏颗粒对儿童湿疹脾虚食湿蕴积证的临床疗效。方法:将符合纳入标准的64例湿疹患儿随机分为治疗组、对照组,治疗组(32例)予克敏颗粒口服,对照组(32例)予氯雷他定颗粒口服,4周为1疗程,各观察1个疗程,并分别于治疗前后观察其中医症候总积分、主症及主症中各症状积分、次症积分和EASI评分。结果:治疗组治愈率68.75%,总有效率93.75%;对照组治愈率40.63%,总有效率87.50%。结果两组治愈率比较P0.05,差异有统计学意义,治疗组优于对照组;总有效率比较P0.05,差异无统计学意义,治疗组与对照组疗效相当。结论:克敏颗粒对儿童湿疹(脾虚食湿蕴积证)有较好疗效,在改善皮损形态、皮损面积及治疗慢性湿疹上优于对照组;且具有复发率低等优点,临床上值得推广。
[Abstract]:Objective: to observe the clinical effect of Kemin granule on children with eczema spleen deficiency and dampness accumulation syndrome. Methods: 64 children with eczema who met the inclusion criteria were randomly divided into treatment group (n = 32), treatment group (n = 32) and loratadine granule (n = 32). The treatment group (n = 32) was treated with loratadine granule for 4 weeks as a course of treatment. The total score of TCM syndrome, the score of main symptom and the score of each symptom, the score of secondary symptom and the score of EASI were observed before and after treatment. Results: the cure rate was 68.75% and the total effective rate was 93.75% in the treatment group and 40.63% and 87.50% in the control group. Results the cure rate of the two groups was significantly higher than that of the control group, and the total effective rate of the treatment group was better than that of the control group, and there was no significant difference between the total effective rate and the control group, and the curative effect of the treatment group was the same as that of the control group. Conclusion: Kemin granule has good curative effect on eczema in children (spleen deficiency and dampness accumulation syndrome), which is superior to the control group in improving the shape of skin lesions, the area of skin lesions and the treatment of chronic eczema, and has the advantages of low recurrence rate, which is worth popularizing in clinic.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R275.9

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