冠心病心绞痛痰热证与纤维蛋白原、D-二聚体的相关性研究

发布时间：2019-06-06 05:15

【摘要】：目的探讨冠心病痰热证与纤维蛋白原(FIB)与D-二聚体之间的相关性。并以此为依据,以利中医辨证论治,确立清热化痰的治疗方法。方法将30例冠心病痰热证患者、30例冠心病痰阻心脉证患者、30例正常对照组用免疫比浊法检测FIB以及D-二聚体,进行统计分析得出结论。结果冠心病痰热证组患者FIB值、D-二聚体水平均高于冠心病痰阻心脉证组,而冠心病痰阻心脉证组FIB值、D-二聚体值均高于正常对照组,冠心病男性患者FIB值高于女性患者,冠心病患者D-二聚体值性别间无统计学意义。结论FIB、D-二聚体值增高与冠心病痰热证相关,两者值增高与冠心病发病相关,男性冠心病患者FIB值高于女性患者,其原因可能与患者抽烟、酗酒等情况有关。
[Abstract]:Objective to investigate the correlation between phlegm-heat syndrome and fibrinogen (FIB) and D-dimer in coronary heart disease (CAD). On this basis, to benefit TCM syndrome differentiation and treatment, establish the treatment method of clearing away heat and dissipating phlegm. Methods FIB and D-dimer were detected by immunoturbidimetry in 30 patients with phlegm-heat syndrome of coronary heart disease, 30 patients with coronary heart disease with phlegm blocking heart and pulse syndrome and 30 normal controls. Results the FIB values and D-dimer levels in the phlegm-heat syndrome group were higher than those in the coronary heart disease phlegm blocking heart syndrome group, while the FIB values and D-dimer values in the coronary heart disease phlegm blocking heart syndrome group were higher than those in the normal control group. The FIB value of male patients with coronary heart disease was higher than that of female patients, but there was no significant difference between sex and sex of D-dimer value in patients with coronary heart disease. Conclusion the increase of FIB,D- dimer value is related to phlegm-heat syndrome of coronary heart disease, and the increase of FIB value is related to the incidence of coronary heart disease. The FIB value of male patients with coronary heart disease is higher than that of female patients, which may be related to smoking and drinking.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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