HBV感染者红外敏感经穴贴敷对病毒载量影响的临床探索

发布时间：2019-07-01 17:25

【摘要】：目的:观察贴敷红外敏感穴位对慢性乙型肝炎(CHB)患者血清中病毒复制的影响。方法:将27例CHB患者设为穴位贴敷治疗组,运用红外敏感穴位贴敷疗法治疗3周;另设空白对照组28例,不采取治疗措施;采用实时荧光定量聚合酶链反应(RT-PCR)法观察两组患者治疗周期前后HBV-DNA定量指标变化情况。结果:1贴敷治疗组患者治疗前后血清中HBV-DNA载量较空白对照组显著降低(P0.05);2贴敷治疗组中初始HBV-DNA载量处于中低水平的患者疗效较好;3贴敷治疗组病毒载量呈次方下降的比例显著高于空白对照组。结论:红外敏感穴位中药贴敷能够有效降低患者乙肝病毒复制量,对提高慢性乙型肝炎患者临床疗效具有积极意义。
[Abstract]:Objective: to observe the effect of infrared sensitive acupoints on virus replication in serum of patients with chronic hepatitis B (CHB). Methods: 27 patients with CHB were divided into acupoint application treatment group and infrared sensitive acupoint application therapy for 3 weeks, 28 patients in blank control group were treated with no treatment measures, and the changes of HBV-DNA quantitative indexes before and after treatment cycle were observed by real-time fluorescence quantitative polymerase chain reaction (RT-PCR). Results: 1 the serum HBV-DNA load in the treatment group was significantly lower than that in the blank control group before and after treatment (P 0.05), the initial HBV-DNA load in the treatment group was better than that in the blank control group, and (3) the proportion of virus load in the treatment group was significantly higher than that in the blank control group. Conclusion: the application of traditional Chinese medicine at infrared sensitive acupoints can effectively reduce the replication of hepatitis B virus in patients with chronic hepatitis B. it is of positive significance to improve the clinical efficacy of patients with chronic hepatitis B.
【作者单位】：辽宁中医药大学研究生学院;辽宁中医药大学针灸推拿学院针灸基础教研室;本溪市第六人民医院检验科;
【基金】：辽宁省自然科学基金(2015020371) 沈阳市科技计划项目(F15-199-1-09)
【分类号】：R246.1

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