图形异同判别ERP技术检测伪装认知损害的研究

发布时间：2018-02-28 21:30

本文关键词： 法医临床学事件相关电位图形异同判别伪装认知损害　出处：《中国法医学杂志》2013年03期 　论文类型：期刊论文

【摘要】：目的探讨图形异同判别ERP范式对鉴别伪装认知损害的法医学价值。方法 40例健康志愿者在合作和伪装认知损害两种情境下,进行二项必选数字记忆测验(BFDMT)及图形异同判别ERP范式检测,对照组为20例合作的三级脑外伤者。结果三组被试完成相同、无关、相似图形刺激后引出的ERP波均包括N1、P2、N2、P3和N3五个成分,三组样本组间的N2、P3和N3的潜伏期和波幅均存在差异。其中,伪装组相同图形的N3潜伏期与正常组无显著性差异,明显短于外伤组(P0.01);伪装组无关图形的N3潜伏期较正常组延长,但短于外伤组,波幅较正常组降低(P0.05);伪装组相似图形的N3潜伏期较正常组和外伤组缩短(P0.01),波幅较正常组降低(P0.01)。以N3潜伏期为指标进行判别分析,探查伪装认知损害的敏感性为81.8%、特异性为76.9%、命中率为79.2%。结论图形异同判别范式可引出稳定的特征性ERP成分,其中N3的波幅和潜伏期有显著的组间差异,对判断伪装认知损害有一定的参考价值。
[Abstract]:Objective to explore the forensic value of ERP paradigm in distinguishing camouflage cognitive impairment in 40 healthy volunteers. The binomial digital memory test (BFDMTT) and the ERP normal pattern of pattern similarities and differences were performed. The control group was 20 cases of third-grade brain trauma. Results the results of the three groups were the same, not the same. The ERP waves induced by similar patterns were all composed of five components: N1P2P2N2OP3 and N3. The latency and amplitude of N2P3 and N3 were different among the three groups, and there was no significant difference in the N3 latency of the same pattern between the camouflage group and the normal group, and there was no significant difference in the N3 latency between the camouflage group and the normal group. The N3 latency in the camouflage group was longer than that in the normal group, but shorter than that in the trauma group. The N3 latency of the camouflage group was shorter than that of the normal group and the trauma group, and the amplitude was lower than that of the normal group. The sensitivity, specificity and hit rate of detecting camouflage cognitive impairment were 81.8, 76.9and 79.2 respectively. Conclusion the pattern pattern of similarity and difference can lead to stable characteristic ERP components, in which there are significant differences in amplitude and latency of N3 between groups. It has certain reference value for judging the impairment of camouflage cognition.
【作者单位】：华中科技大学同济医学院法医学系;武汉市公安局东新分局刑侦大队;
【基金】：湖北省自然科学基金课题项目(20091883)
【分类号】：D919

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