利用增龄性定量指标判定华中地区青少年生理年龄的研究

发布时间：2018-06-14 00:12

本文选题：生理年龄 + 年龄判定　；参考：《华中科技大学》2010年博士论文

【摘要】： 在口腔医学及法医学研究领域,青少年个体生理年龄的判定方法研究已成为该学科的前沿课题,寻找一种合适准确的判定方法对于法医学个体鉴别以及口腔医学的研究有相当大的帮助。一直以来,大量的研究集中在如何利用不同的指标进行个体生理年龄判定系统的研究上。对于青少年人群采用的基本都是牙龄及骨龄的相关性增龄指标,并且相关的判定方法一般均采用图形判定法,由于选取的指标的不同以及判定者本身理论基础的不同导致判定的结果准确度有很大的差异,误差较大。本文在对国内外具有代表性的个体生理年龄判定方法研究发展进行总结综述的基础上,系统的论述了采用定量化指标判定华中地区青少年人群个体生理年龄的理论和方法。个体的生理性增龄指标主要集中在第三磨牙,颈椎,及牙根成熟指数这几个指标,本文试图通过这几项指标的定量化,探讨新的个体年龄的判定方法。第一部分利用Demirjian法判定第三磨牙发育程度,通过量表评分使其定量化；通过评分系统按照性别差异将其定量化,并推导其判定公式。第二部分利用计算机系统建立第三、四颈椎的增龄性发育指标的定量化方法,主要定量化指标集中在颈椎椎体的高度(vertebral body height (AH), vertebral body height (H),posterior vertebral body height (PH))这三个指标,利用逐步线性回归方法推导出个体年龄的判定公式。第三部分利用全口曲面断层片上发育牙齿的牙齿发育成熟指数建立关于牙齿发育增龄性指标的定量化方法,同时利用逐步线性回归方法推导出个体年龄的判定公式。建立第三磨牙发育阶段定量化指标与个体生理年龄之间的判定公式(公式1)：男性：Age=8.33+1.51 Development stage 女性：Age=9.10+1.43 Development stage 建立利用第三、四颈椎的增龄性发育的定量化指标与个体生理年龄之间的判定公式(公式2)：男性：Age=-0.528+4.534PH/AP3+1.463AH/H4+5.364AH/AP3-1.894 AH/PH4 +3.345AH/H3 女性：Age=1.679+5.503AH/AP3+3.432AH/H4+3.528H/P-3.278 PH/AP4+2.502 AH/H3 建立利用牙齿根尖孔的宽度的定量化指标与个体生理年龄之间的判定公式(公式3)：Age=9.231-0.723 N0-1.588X5+0.592S-0.099 s·N0 第四部分将其上三组判定公式用于判定青少年人群的生理年龄,比较其三种方法的适用范围。针对不同年龄人群以上三种判定方法准确度并不相同,青少年(8-10岁)早期公式3的判定效果较好,发育生长高峰期(11-13岁)公式2比较合适,青春期晚期(15-18岁)公式1效果最佳。综上所述,青春期个体的发育过程中的增龄性改变对于判定个体的生理年龄具有较佳的结果,定量化这些指标后可以大大提高判定结果的准确性。同时针对青春期的不同年龄人群也应在粗略估计年龄的基础上选用较为合适的定量化增龄指标进行个体生理年龄的判定。
[Abstract]:In the field of stomatology and forensic medicine, the study of the method of determining the individual physiological age of teenagers has become the frontier subject of this discipline. Finding a suitable and accurate method is of great help to the individual identification of forensic medicine and the study of stomatology. A large number of studies have been focused on how to use different indicators to determine the individual physiological age system. For young people, the basic is the age of teeth and bone age related to the aging index, and the related methods are generally used to determine the figure of the method, Because of the difference of the selected indexes and the different theoretical basis of the judge itself, the accuracy of the judgment results is very different, and the error is large. On the basis of summing up the research and development of representative individual physiological age determination methods at home and abroad, this paper systematically discusses the theory and method of using quantitative indexes to determine the individual physiological age of teenagers in central China. The physiological aging indexes of individuals are mainly in the third molar, cervical vertebrae and root maturation index. This paper attempts to discuss the new method of judging individual age through the quantification of these indexes. The first part uses Demirjian method to judge the development degree of the third molar, quantifies the third molar by rating scale, quantifies it according to the gender difference through the scoring system, and deduces its judging formula. The second part uses the computer system to establish the quantitative method of aging development index of the third and fourth cervical vertebrae. The main quantitative indexes focus on the three indexes of cervical vertebral body height and vertebral body height. The method of stepwise linear regression is used to deduce the determination formula of individual age. In the third part, the quantitative method of tooth development aging index is established by using the tooth development maturity index of the tooth on the whole surface section, and the determination formula of individual age is deduced by using the stepwise linear regression method. Establish a formula for determining the relationship between the quantitative indices of the development stage of the third molar and the physiological age of the individual (formula 1: male: 8. 33 1.51 stage female: age 9.10 1.43 Development stage) Third, Formula for determining Aging Development of the four Cervical vertebrae and individual physiological Age (Formula 2: male:% Age-0.528 4.534 PHP 3 1.463AH / P H45.364AH / AP3-1.894 AH- / PH43.345AH / H3 female: age 1.679 5.503AHAP3 3.432AHP 3.528Hp / P-3.278 AP4 2.502 AH / H _ 3 established the determination formula between the width of apical foramen and the physiological age of individual (formula 3):Age=9.231-0.723 N0-1.588X5 0.592S-0.099s N0) the fourth part determined the upper three groups of the male by using the quantitative index of apical foramen width and individual physiological age (formula 3):Age=9.231-0.723 N0-1.588X5 0.592S-0.099s N0). The formula is used to determine the physiological age of teenagers, The scope of application of the three methods is compared. The accuracy of the above three methods is not the same. The effect of early formula 3 is better, the peak growth period of development is 11-13 years old (2) formula 2 is more suitable, and the late puberty period is 15-18 years old) formula 1 is the best. To sum up, the aging changes in the development of puberty individuals have a better result in determining the physiological age of individuals, and the accuracy of the results can be greatly improved by quantifying these indicators. At the same time, according to the different ages of puberty, we should choose a more suitable quantitative aging index to judge the individual physiological age on the basis of rough estimation of age.
【学位授予单位】：华中科技大学
【学位级别】：博士
【学位授予年份】：2010
【分类号】：D919.4

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