血液不同稀释状态下凝血功能的变化

发布时间：2018-03-09 10:11

本文选题：血栓弹力描记图　切入点：凝血　出处：《中国输血杂志》2016年07期 　论文类型：期刊论文

【摘要】：目的探讨血液不同稀释状态下凝血功能的变化。方法选取2015年1-6月于我科行血栓弹力图检测且结果正常的患者30例,进一步应用0.9%Na Cl溶液以20%,40%,60%,80%的稀释度进行稀释,测定在不同稀释度下TEG各个指标[反应时间(R),血凝块形成的时间(K),α角(α),最大振幅(MA)]的变化,并进行统计分析。结果稀释度20%时,R值缩小,与基础值有显著性差异(P0.05),K值、α角、MA值与基础值相比差异均无统计学意义(P0.05);稀释度40%时,R值与基础值差异无统计学意义(P0.05),K值增大、α角缩小、MA值缩小均与基础值有显著性差异(P0.05);稀释度60%时,R值与基础值差异无统计学意义(P0.05),K值增大、α角缩小、MA值缩小均与基础值有显著性差异(P0.05);稀释度80%时,R值增大,与基础值有显著性差异(P0.05),K值增大,甚至测不出数值,α角缩小、MA值缩小与基础值有显著性差异(P0.05)。结论血液稀释至残余量40%时,凝血功能逐渐降低。
[Abstract]:Objective to investigate the changes of coagulation function in different hemodilution states. Methods Thirty patients with normal thromboelastography from 2015 to June were selected and further diluted with 0.9 NaCl solution with a dilution of 20% and 6080%. The changes of TEG indexes (reaction time, time of clot formation, 伪 angle (伪 n, maximum amplitude MAA)) were determined at different dilutions, and statistical analysis was carried out. Results the R value of TEG decreased when dilution was 20. There was significant difference with the basic value (P 0.05 / K), there was no significant difference between the 伪 -angle MA value and the base value (P 0.05), and there was no significant difference between the R value and the base value at the dilution level of 40% (P < 0.05), and the decrease of the 伪 -angle decreased MA value was significantly higher than that of the base value. There was no significant difference between the R value and the base value when the dilution degree was 60. There was no significant difference between the R value and the base value. There was a significant difference between the 伪 angle reduction and the base value, and there was a significant difference between the 伪 angle reduction and the base value (P 0.05), and at the dilution of 80%, the R value increased. There was significant difference between the basic value and the basic value (P 0.05), even the value of K could not be measured. There was a significant difference between the reduction of 伪 angle and the basic value (P 0.05). Conclusion the coagulation function decreases gradually when the hemodilution reaches 40%.
【作者单位】：中国石油天然气集团公司中心医院输血科;河北廊坊市医学科学情报站;
【分类号】：R457.1

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