荧光定量PCR检测淋球菌、沙眼衣原体和解脲脲原体结果分析

发布时间：2018-03-16 10:13

本文选题：淋球菌　切入点：沙眼衣原体　出处：《中国人兽共患病学报》2016年03期 　论文类型：期刊论文

【摘要】：目的了解延安市皮肤性病科门诊患者泌尿生殖道淋球菌(NG)、沙眼衣原体(CT)及解脲脲原体(UU)的感染现状及其特点,为临床提供依据。方法采用实时荧光聚合酶链式反应技术(FQ-PCR)对784例患者的泌尿生殖道分泌物的NG、CT和UU核酸进行检测。结果 784例患者中,NG、CT和UU的阳性检出率分别为15.43%、34.69%和30.87%,女性UU感染率明显高于男性(P0.01),男性CT感染率明显高于女性(P0.05),NG感染率男性虽高于女性,但无性别差异(P0.05)。混合感染检出率为19.64%,其中CT+UU双重感染的阳性检出率最高,为10.20%。不同年龄感染情况显示,感染率以21~40岁年龄段最高。结论泌尿生殖道感染患者NG、CT和UU阳性检出率不尽相同,阳性患者大多年龄在青壮年时期,应作为性传播疾病防治工作中的重点对象。混合感染较为常见,临床应进行3种病原体的检测。
[Abstract]:Objective to investigate the infection status and characteristics of gonococcus gonorrhoeae (NGN), chlamydia trachomatis (CTT) and Ureaplasma Urealyticum (UU) in urogenital tract patients in Yan'an City. Methods to detect NGCT and UU nucleic acid in genitourinary secretions of 784 patients by real-time fluorescent polymerase chain reaction (FQ-PCR). Results the positive rates of NGCT and UU were detected in 784 patients. The infection rate of UU in females was significantly higher than that in males (P 0.01). The infection rate of CT in males was significantly higher than that in females, although the infection rate in males was higher than that in females. But there was no sex difference (P 0.05). The detection rate of mixed infection was 19.64. The positive rate of CT UU double infection was the highest (10.20%). Conclusion the positive rates of NGCT and UU in patients with genitourinary tract infection are different. It should be regarded as the key object in the prevention and treatment of sexually transmitted diseases. The mixed infection is more common and the clinical detection of three pathogens should be carried out.
【作者单位】：延安大学医学院;延安大学附属医院;
【基金】：陕西省教育厅科研项目(No.14JK1836) 延安大学青年专项基金资助项目(No.YDQ2013-03) 陕西省大学生创新创业训练计划项目(No.1415)~~
【分类号】：R440

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