脓毒血症患者血清氨基末端脑钠肽前体和白细胞介素-6、-18的表达及意义

发布时间：2018-05-31 04:49

本文选题：脓毒血症 + NT-pro　；参考：《中国老年学杂志》2016年22期

【摘要】：目的检测脓毒血症患者血清中氨基末端脑钠肽前体(NT-pro BNP)和白细胞介素(IL)-6、IL-18的表达,关注其临床意义。方法57例脓毒血症患者的血清标本作为观察组,21例经体检证实无明显器质性疾病的成人血清标本作为对照组,检测两组血清中NT-pro BNP、IL-6和IL-18的表达。结果两组中NT-pro BNP、IL-6和IL-18的表达差异有统计学意义。观察组中NT-pro BNP、IL-6和IL-18的表达与患者预后相关。相关分析显示观察组中NT-pro BNP、IL-6和IL-18的表达无相关性。结论脓毒血症患者血清中NT-pro BNP、IL-6和IL-18高表达,在病变形成和进展中可能有一定作用。
[Abstract]:Objective to detect the expression of NT-pro BNPs and IL-18 in serum of patients with sepsis. Methods the serum samples of 57 patients with sepsis were used as control group. The expression of IL-6 and IL-18 in serum of 21 adult patients with no obvious organic diseases was detected. Results there was significant difference in the expression of NT-pro BNPP IL 6 and IL-18 between the two groups. The expression of NT-pro BNPP IL 6 and IL-18 was correlated with the prognosis of the patients in the observation group. Correlation analysis showed that there was no correlation between the expression of NT-pro BNPP IL 6 and IL-18 in the observation group. Conclusion the high expression of IL-6 and IL-18 in serum of patients with sepsis may play a role in the formation and progression of lesions.
【作者单位】：青海大学附属医院急诊外科;
【分类号】：R459.7

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