慢性化脓性中耳炎患者耳道分泌物病原菌培养及药敏结果分析

发布时间：2018-09-17 17:28

【摘要】：目的分析慢性化脓性中耳炎患者耳道分泌物病原菌培养及药敏结果,为慢性化脓性中耳炎治疗治疗提供参考。方法选取慢性化脓性中耳炎100例(113耳),行耳道分泌物细菌培养及药敏试验。结果 87耳检出病原菌90株,其中革兰阳性菌47株、革兰阴性菌39株、真菌4株,病原菌构成比金黄色葡萄球菌15.56%、表皮葡萄球菌15.56%、铜绿假单胞菌14.44%、凝固酶阴性葡萄球菌8.89%、肺炎克雷伯菌8.89%、粪肠球菌7.78%、变形杆菌6.67%、大肠埃希菌4.44%;金黄色葡萄球菌对苯唑西林、替考拉宁和利奈唑胺完全敏感,表皮葡萄球菌对头孢唑林、美罗培南、苯唑西林、替考拉宁、利奈唑胺完全敏感,铜绿假单胞菌对美罗培南、亚胺培南、氨曲南、多黏菌素B、哌拉西林、舒普深完全敏感。结论慢性化脓性中耳炎患者耳道分泌物的常见病原菌为金黄色葡萄球菌、表皮葡萄球菌、铜绿假单胞菌、凝固酶阴性葡萄球菌及肺炎克雷伯菌,临床多种常用抗菌药物对以上病原菌敏感性较高。
[Abstract]:OBJECTIVE To analyze the culture and drug sensitivity of pathogenic bacteria in otitis media secretions of patients with chronic suppurative otitis media, and to provide reference for the treatment of chronic suppurative otitis media.Methods 100 cases (113 ears) of chronic suppurative otitis media were selected for bacterial culture and drug sensitivity test. Gram-negative bacteria 39 strains, fungi 4 strains, the composition of pathogenic bacteria than Staphylococcus aureus 15.56%, Staphylococcus epidermidis 15.56%, Pseudomonas aeruginosa 14.44%, coagulase-negative Staphylococcus 8.89%, Klebsiella pneumoniae 8.89%, Enterococcus faecalis 7.78%, Proteus 6.67%, Escherichia coli 4.44%; Staphylococcus aureus paraoxacillin, Teicoplanin and Lily Nezolamide was completely sensitive, Staphylococcus epidermidis was completely sensitive to cefazolin, meropenem, oxacillin, teicoplanin, linezolamide, and Pseudomonas aeruginosa was completely sensitive to meropenem, imipenem, aztreonam, polymyxin B, piperacillin and sulpiride. Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, coagulase-negative Staphylococcus and Klebsiella pneumoniae are commonly used in clinical antibiotics with high sensitivity to the above pathogens.
【作者单位】：南阳市中心医院;郑州大学药学院;
【基金】：国家自然科学基金资助项目(30901778)
【分类号】：R764.21;R446.5

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