低氧舱睡眠结合运动与饮食控制对肥胖青少年食欲调节激素的影响

发布时间：2018-05-22 07:24

本文选题：低氧 + 运动与饮食控制　；参考：《上海体育学院》2015年硕士论文

【摘要】：研究目的:本研究以肥胖青少年为研究对象,比较低氧舱睡眠结合运动与饮食控制和单纯运动与饮食控制减肥效果以及受试者血浆食欲调节激素水平的差异,分析低氧舱睡眠对肥胖青少年食欲调节激素的影响,为低氧舱睡眠结合运动与饮食控制的减肥方式提供科学依据。研究方法:将35名超重和肥胖青少年随机分为对照组(19人)和实验组(16人)进行为期4周的干预。对照组采用有氧运动结合饮食控制的传统减肥方式,根据受试者的健康状况和运动负荷试验确定运动强度,制定个性化的运动处方,营养师根据受试者的基础代谢率制定合理的饮食方案,保证热量和必需营养物质的供给。实验组除进行与对照组相同的运动与饮食控制干预外,受试者每日夜间于低氧舱内眠,低氧环境为模拟海拔2700米高度,每日睡眠时间为10小时。干预前、后分别检测受试者形态学指标及血浆食欲调节激素(Insulin,Leptin,Ghrelin,PYY,CCK,GLP-1,MCP-1)水平。研究结果:(1)干预后,两组受试者体重、BMI、体脂含量、腰臀比、舒张压、安静心率均显著低于干预前水平(p0.01);对照组干预后收缩压低于干预前水平(p0.01),而实验组干预前后无显著性差异(p0.05)。干预后,实验组体重变化率和BMI下降程度均显著大于对照组(p0.05),而其他形态学指标变化量组间无显著差异(p0.05)。干预后,实验组男性受试者体重变化率和BMI下降程度均显著高于对照组(p0.05),实验组女性受试者各项形态学指标变化量与对照组相比均无显著差异(p0.05)。(2)干预后,对照组血浆Insulin水平显著低于干预前(p0.01),实验组干预前后无显著性差异(p0.05),且Insulin水平的变化量组间存在显著性差异(p0.05);干预后两组Leptin水平均显著低于干预前(p0.01),但对照组Leptin水平的下降程度显著大于实验组(p0.05);干预后,实验组Ghrelin水平显著高于干预前(p0.05),对照组干预前后无显著性差异(p0.05),且Ghrelin水平的变化量组间无显著性差异(p0.05);干预后,对照组CCK水平显著下降(p0.05),实验组CCK水平无显著变化(p0.05),且CCK水平的变化量组间存在显著性差异(p0.05);对照组MCP-1呈下降趋势,实验组MCP-1呈升高趋势,且MCP-1水平的变化量组间存在显著性差异(p0.05)。(3)男性受试者:干预后,对照组Insulin水平呈下降趋势,实验组Insulin水平呈上升趋势,Insulin变化量组间存在显著性差异(p0.05);对照组PYY水平呈下降趋势,实验组PYY水平呈上升趋势,PYY水平变化量组间存在显著性差异(p0.05);两组CCK水平均呈下降趋势,实验组下降程度显著小于对照组(p0.05)。女性受试者:干预后实验组各项食欲调节激素水平与对照组均无显著性差异(p0.05)。研究结论:(1)单纯运动与饮食控制和低氧舱睡眠结合运动与饮食控制均可显著降低肥胖青少年体重、BMI和体脂含量;相比之下,低氧舱睡眠结合运动与饮食控制对肥胖青少年减肥效果更有利。(2)运动结合饮食控制的减肥方式在起到减、控体重效果的同时使肥胖青少年血浆食欲抑制激素(CCK,Insulin,Leptin)水平下降,可能导致受试者食欲增强;而低氧舱睡眠结合运动与饮食控制可通过维持食欲抑制激素(Insulin,Leptin,CCK)的水平改善单纯运动结合饮食控制导致食欲增强的状况,可能更有利于肥胖青少年减重过程中食欲的控制。(3)低氧舱睡眠结合运动与饮食控制的减肥方式对肥胖青少年形态学和食欲调节激素指标的影响存在性别差异,男性肥胖青少年形态学(体重,BMI)和食欲调节激素指标(Insulin,PYY,CCK)受低氧舱睡眠刺激的影响更为显著,应根据实际情况选择性使用。
[Abstract]:Objective: To compare the effects of sleep binding exercise, diet control, diet control, diet control and diet control, and the difference in the level of plasma appetite regulating hormones in the subjects, and to analyze the effects of hypoxia on the appetite of obese adolescents and the sleep binding activity of the hyperoxygen chamber. 35 overweight and obese adolescents were randomly divided into the control group (19 people) and the experimental group (16 people) for 4 weeks. The control group adopted the traditional diet control method with aerobic exercise combined with diet control, and determined exercise according to the health status of the subjects and exercise load test. The dietitians make a reasonable diet plan according to the basal metabolic rate of the subjects to ensure the supply of heat and essential nutrients. In addition to the same exercise and diet control intervention with the control group, the experimental group sleep at night in the hypoxia compartment and the hypoxic environment is 2700 meters high. Degree, daily sleep time was 10 hours. Before intervention, the morphological indexes of subjects and plasma appetite regulating hormone (Insulin, Leptin, Ghrelin, PYY, CCK, GLP-1, MCP-1) were measured respectively. The results were as follows: (1) after the intervention, the body weight, BMI, body fat content, waist to hip ratio, diastolic pressure and quiet heart rate of the two subjects were significantly lower than those before intervention (P0.01); After intervention, the systolic pressure was lower than that before intervention (P0.01), but there was no significant difference between the experimental group before and after intervention (P0.05). The weight change rate and the decrease degree of BMI in the experimental group were significantly greater than those in the control group (P0.05), but there was no significant difference between the changes of other morphological indexes (P0.05). The prognosis of the male subjects in the experimental group was not significant (P0.05). The degree of decrease in BMI was significantly higher than that of the control group (P0.05). There was no significant difference in the changes of the morphological indexes between the experimental group and the control group (P0.05). (2) the plasma Insulin level in the control group was significantly lower than that before the intervention (P0.01), and there was no significant difference before and after the intervention (P0.05) in the experimental group (P0.05), and the changes of the Insulin level were between the groups. There was significant difference (P0.05). The level of Leptin in two groups was significantly lower than that before intervention (P0.01), but the level of Leptin in the control group was significantly greater than that in the experimental group (P0.05); the Ghrelin level in the experimental group was significantly higher than that before the intervention (P0.05), and there was no significant difference (P0.05) in the control group before and after the dry pre intervention (P0.05), and the variation of the level of Ghrelin was between the groups. There was no significant difference (P0.05); the level of CCK in the control group decreased significantly (P0.05), and there was no significant change in the level of CCK in the experimental group (P0.05), and there was a significant difference between the changes of the CCK level (P0.05); the control group MCP-1 showed a downward trend, and the MCP-1 in the experimental group increased, and there was a significant difference (P0.05) between the MCP-1 levels. (3) Male subjects: the Insulin level in the control group showed a downward trend, the level of Insulin in the experimental group showed an upward trend, and there was a significant difference between the Insulin changes (P0.05), the level of PYY in the control group was declining, the PYY level in the experimental group was rising, the PYY level was significantly different (P0.05), and the two groups of CCK were all lower. The decreasing degree of the experimental group was significantly lower than that of the control group (P0.05). There was no significant difference in the level of appetite regulating hormone between the experimental group and the control group (P0.05). (1) the study conclusions: (1) simple exercise and diet control and low oxygen chamber sleep combined transport and diet control can significantly reduce the weight of obese adolescents, BMI and In contrast, the sleep binding and diet control of the low oxygen chamber is more beneficial to obese adolescents. (2) the way of reducing weight loss with diet control and reducing the level of CCK, Insulin, Leptin in obese adolescents may lead to increased appetite. The sleep binding exercise and diet control in the hypoxic chamber can improve the condition of appetite enhancement through the maintenance of appetite suppressor hormone (Insulin, Leptin, CCK) and diet control, which may be more beneficial to the control of appetite in the weight loss process of obese adolescents. (3) low oxygen chamber sleep combined exercise and diet controlled weight loss methods There is a gender difference in the effects of morphologic and appetite regulating hormone indicators in obese adolescents. The morphological (weight, BMI) and appetite regulating hormone indicators (Insulin, PYY, CCK) of male obese adolescents are more affected by the sleep stimulation of the hyperoxygen chamber, and should be selected according to the actual conditions.
【学位授予单位】：上海体育学院
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：G804.2

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