甲基硅氧烷在海洋生物中的生物放大效应研究
发布时间：2019-04-17 10:16
【摘要】：甲基硅氧烷是以硅氧(Si-O)键为主键,硅原子上直接连接甲基基团的有机硅化合物,具有链状和环状两类结构(分别以L。和D。表示,n表示化合物分子中Si原子的个数),广泛应用于人们的日常生活用品中。研究表明甲基硅氧烷可能具有持久性、生物富集性及生物毒性,因而被列为潜在的持久性有毒物质,受到广泛关注,但是,已有研究结果对甲基硅氧烷是否存在生物放大效应存在争议。带着上述问题,本论文以大连湾海域为研究区域,利用稳定氮和碳同位素分析了主要生物间的营养关系,建立不同生物种类体内受试化合物脂肪当量浓度与营养级之间的线性回归模型,分析受试化合物在海洋食物网中的生物放大效应。结果表明,D5在不同物种内的脂肪当量浓度与营养级水平之间具有极显著的正相关关系(R=0.44,p0.0001),证明其在所研究的食物网中存在潜在的生物放大效应。利用建立的回归模型,通过计算得到D5的营养级放大系数(TMF)为1.77,统计分析得到95%置信区间的(95%CI)取值范围是1.41-2.24,利用10000次的蒙特-卡洛模拟得到D5的TMF1的概率为99.8%(TMF1说明营养级放大效应存在)。类似的脂肪当量浓度与营养级水平之间正相关关系对于D4、D6和D7三种化合物并不显著(D4：R=0.14,p=0.16；D6：R=0.01,p=0.92；D7：R=-0.15,p=0.12)。利用相同的方法计算得到D4的TMF为1.16(95%CI: 0.94-1.44；TMF1的概率是94.7%)；D6的TMF为1.01(95%CI：0.84-1.22；TMF1的概率是66.9%)；D7的TMF为0.85(95%CI：0.69-1.04,；TMF1的概率是48.6%)。此外,本研究以一种被证明具有显著生物放大效应的化合物：2,2’,4,4’,5-五溴联苯醚(BDE-99)作为基准化合物,进行比较研究。结果表明,BDE-99在不同物种内的脂肪当量浓度与营养级水平之间具有极显著的正相关关系(R=0.65,p0.0001),计算得到其TMF值为3.27(95%CI：2.49-4.30；TMF1的概率是99.7%)。
[Abstract]:Methyl siloxane is an organosilicon compound with Si-O bond as the main bond and methyl group directly connected to the silicon atom. It has two kinds of structure, i.e., chain structure and ring structure (L, L). And D. N denotes the number of Si atoms in compound molecules, which is widely used in people's daily necessities. Studies have shown that methylsiloxane may be persistent, bioenriched and biologically toxic and is classified as a potentially persistent toxic substance that is of wide concern, however, There is controversy about the biomagnification effect of methylsiloxane. With the above problems in mind, the nutrient relationships among the main organisms were analyzed by using stable nitrogen and carbon isotopes in Dalian Bay as the study area. A linear regression model between fat equivalent concentration and nutrient level of tested compounds in different biological species was established and the biomagnification effects of tested compounds in marine food webs were analyzed. The results showed that there was a very significant positive correlation between the fat equivalent concentration of D5 in different species and the nutrient level (R = 0.44, p 0.0001), which indicated that D5 had potential biomagnification effect in the food webs studied. Using the established regression model, the trophic magnification factor (TMF) of D5 is calculated to be 1.77, and the range of 95% confidence interval (95%CI) is 1.41 to 2.24, by statistical analysis. The probability of obtaining TMF1 of D5 from 10000 Monte-Carlo simulations is 99.8% (TMF1 indicates the existence of nutrient-level amplification effect). A positive correlation between similar fat equivalent concentration and nutrient level was not significant for D4, D6 and D7 compounds (D4R0.14, p16D6 / R0.01, p = 0.92D7 / R = 0.15, p = 0.12), and there was no significant correlation between D4, D6 and D7 (D4R = 0.14, p = 0.16 / D6 / R = 0.01, p = 0.92d7 / R = 0.15, p = 0.12). Using the same method, the TMF of D4 was 1.16 (95% CI: 0.94%), and the TMF of D6 was 1.01 (95% CI 0.84? 1.22? TMF1 was 66.9%), and the TMF of D6 was 1.01 (95% CI: 0.94? 1.44? TMF1 was 94.7%), while that of D6 was 1.01 (95% CI: 0.94? 1.44). The TMF of D7 is 0.85 (95% CI / 0.69? 1.04, the probability of TMF1 is 48.6%). In addition, a reference compound, 2,2, 4, 4, 5-pentabromobiphenyl ether (BDE-99), was used as a reference compound in this study, which proved to have significant biomagnification effects. The results showed that there was a significant positive correlation between the fat equivalent concentration of BDE-99 in different species and the nutrient level (R = 0.65, p 0.0001), and the TM value was 3.27 (95% CI = 2.49 / 4.30). The probability of TMF1 is 99.7%.
【学位授予单位】：大连海事大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：X171.5
本文编号：2459339
[Abstract]:Methyl siloxane is an organosilicon compound with Si-O bond as the main bond and methyl group directly connected to the silicon atom. It has two kinds of structure, i.e., chain structure and ring structure (L, L). And D. N denotes the number of Si atoms in compound molecules, which is widely used in people's daily necessities. Studies have shown that methylsiloxane may be persistent, bioenriched and biologically toxic and is classified as a potentially persistent toxic substance that is of wide concern, however, There is controversy about the biomagnification effect of methylsiloxane. With the above problems in mind, the nutrient relationships among the main organisms were analyzed by using stable nitrogen and carbon isotopes in Dalian Bay as the study area. A linear regression model between fat equivalent concentration and nutrient level of tested compounds in different biological species was established and the biomagnification effects of tested compounds in marine food webs were analyzed. The results showed that there was a very significant positive correlation between the fat equivalent concentration of D5 in different species and the nutrient level (R = 0.44, p 0.0001), which indicated that D5 had potential biomagnification effect in the food webs studied. Using the established regression model, the trophic magnification factor (TMF) of D5 is calculated to be 1.77, and the range of 95% confidence interval (95%CI) is 1.41 to 2.24, by statistical analysis. The probability of obtaining TMF1 of D5 from 10000 Monte-Carlo simulations is 99.8% (TMF1 indicates the existence of nutrient-level amplification effect). A positive correlation between similar fat equivalent concentration and nutrient level was not significant for D4, D6 and D7 compounds (D4R0.14, p16D6 / R0.01, p = 0.92D7 / R = 0.15, p = 0.12), and there was no significant correlation between D4, D6 and D7 (D4R = 0.14, p = 0.16 / D6 / R = 0.01, p = 0.92d7 / R = 0.15, p = 0.12). Using the same method, the TMF of D4 was 1.16 (95% CI: 0.94%), and the TMF of D6 was 1.01 (95% CI 0.84? 1.22? TMF1 was 66.9%), and the TMF of D6 was 1.01 (95% CI: 0.94? 1.44? TMF1 was 94.7%), while that of D6 was 1.01 (95% CI: 0.94? 1.44). The TMF of D7 is 0.85 (95% CI / 0.69? 1.04, the probability of TMF1 is 48.6%). In addition, a reference compound, 2,2, 4, 4, 5-pentabromobiphenyl ether (BDE-99), was used as a reference compound in this study, which proved to have significant biomagnification effects. The results showed that there was a significant positive correlation between the fat equivalent concentration of BDE-99 in different species and the nutrient level (R = 0.65, p 0.0001), and the TM value was 3.27 (95% CI = 2.49 / 4.30). The probability of TMF1 is 99.7%.
【学位授予单位】：大连海事大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：X171.5
【参考文献】
相关期刊论文 前1条
1 ;加拿大发现两种硅氧烷有毒对中国影响巨大[J];有机硅氟资讯;2009年05期
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