近15年来基因芯片技术在针灸研究中的应用

发布时间：2018-04-02 03:05

本文选题：基因芯片　切入点：针灸研究　出处：《中国针灸》2017年12期

【摘要】：探讨基因芯片技术在针灸学领域研究中的应用概况,为揭示针灸调控机体的作用机制提供科学依据。收集Pub Med、Springer、中国知网(CNKI)、万方(WANFANG)数据库中自2001至2016年有关基因芯片技术在针灸学领域研究中应用的文献,对其进行归纳、概括、分析。发现基因芯片技术在针灸研究中取得了一定的成果,主要集中在经穴脏腑相关性研究、针灸作用的影响因素研究、针灸镇痛的效应与机制研究、针灸延缓衰老的机制研究、针灸治疗各系统疾病的效应与机制研究5个方面。基因芯片技术在揭示针灸作用机制的研究中发挥了重要作用,成为针灸基因组学研究的重要技术手段,但存在成本高、数据挖掘不充分、观察对象不统一、专门人才不足等问题,有待于研究者们进一步解决以加强此技术在针灸领域研究中的推广应用。
[Abstract]:To explore the application of gene chip technology in the field of acupuncture and moxibustion, and to provide scientific basis for revealing the mechanism of acupuncture and moxibustion regulating organism.From 2001 to 2016, the literatures about the application of gene chip technology in the field of acupuncture and moxibustion were collected, summarized and analyzed in the Pub Meder, CNKIN, Wanfang WANFANGS database.It is found that gene chip technology has made some achievements in acupuncture and moxibustion research, which mainly focuses on the research on the correlation of acupoints and viscera, the influencing factors of acupuncture and moxibustion, the effect and mechanism of acupuncture and moxibustion analgesia, and the mechanism of acupuncture and moxibustion on delaying senescence.The effects and mechanisms of acupuncture and moxibustion on various systemic diseases were studied in five aspects.Gene chip technology has played an important role in revealing the mechanism of acupuncture and moxibustion, and has become an important technical means in the research of acupuncture genomics, but it has high cost, insufficient data mining and inconsistent observation objects.The problems of shortage of specialized talents need to be solved further to strengthen the popularization and application of this technique in the field of acupuncture and moxibustion.
【作者单位】：北京中医药大学;
【基金】：国家自然科学基金资助项目:81373727,81574069 北京市自然科学基金资助项目:81574069 中央高校基本科研资助项目:2016-JYB-XS133
【分类号】：R245

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