血流感染人葡萄球菌及其耐消毒剂基因检测

发布时间：2018-10-19 13:16

【摘要】：目的了解医院住院患者血流感染人葡萄球菌临床特点及其耐消毒剂基因携带情况。方法采用回顾性分析方法和基因检测技术,对河北医科大学第二医院住院患者血标本中分离人葡萄球菌及其抗消毒剂基因进行调查与检测。结果连续3年,该医院从患者送检的血标本中共检出病原菌2 897株,其中检出人葡萄球菌596株,占检出病原菌总数的20.57%,标本主要来自各科室重症监护室和呼吸科。所检出的耐甲氧西林人葡萄球菌对抗菌药物耐药率显著高于甲氧西林敏感菌株。从93株血流感染人葡萄球菌中检出32株携带耐消毒剂基因qac A/B,检出率为34.4%。结论该医院住院患者送检血标本中人葡萄球菌检出率最高,严重耐药和抗消毒剂基因检出率均较高。
[Abstract]:Objective to investigate the clinical characteristics of staphylococcus aureus infected by blood flow and the carrying of disinfectant gene in hospitalized patients. Methods retrospective analysis and gene detection techniques were used to investigate and detect the genes of human staphylococcus and its antidisinfectant in blood samples of patients in the second Hospital of Hebei Medical University. Results for 3 consecutive years, 2897 strains of pathogenic bacteria were detected from blood samples of the patients, of which 596 strains of staphylococcus were detected, accounting for 20.57% of the total number of pathogens detected. The samples were mainly collected from intensive care units and respiratory departments in various departments. The antimicrobial resistance of methicillin-resistant staphylococcus was significantly higher than that of methicillin-sensitive strains. 32 of 93 strains of staphylococcus were found to be carrying disinfectant resistant gene qac A / B, and the detection rate was 34. 4%. Conclusion the detection rate of staphylococcus human was the highest, and the detection rate of severe drug resistance and antidisinfectant gene was higher in the blood samples of inpatients in this hospital.
【作者单位】：河北医科大学第二医院;
【基金】：河北省科技厅指导性计划(152777238)
【分类号】：R446.5

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