不同鸡品种NFKB1基因SNPs筛选与进化分析
发布时间：2019-06-15 20:45
【摘要】：以27个鸡品种为试验材料,通过目标捕获测序技术检测NFKB1基因SNPs位点多态性,分析鸡NFKB1基因的遗传效应;通过最大简约法进行系统进化树构建,探讨NFKB1基因的多态性与不同鸡品种的关系。结果表明:27个鸡品种的NFKB1基因上共存在233个突变位点,其中外显子存在6个突变位点,显示出丰富的基因多态性;外显子14上的SNPs位点特异性存在于隐性白羽鸡和AA鸡,并引起了相应的氨基酸变化,该位点可作为这一基因的特异性候选位点。同时,NFKB1基因在外来鸡品种与地方鸡品种、蛋用型与肉用型鸡品种间存在差异,为进一步研究不同鸡品种间的差异提供参考资料。
[Abstract]:The SNPs polymorphism of NFKB1 gene was detected by target capture and sequencing technique in 27 chicken breeds, and the genetic effect of NFKB1 gene was analyzed, and the relationship between NFKB1 gene polymorphism and different chicken breeds was discussed by constructing phylogenetic tree by maximum reduction method. The results showed that there were 233mutation sites in NFKB1 gene of 27 chicken breeds, of which 6 mutation sites existed in exons, showing rich gene polymorphism, and the SNPs loci in exon14 existed specifically in recessed white feather chickens and AA chickens, and caused corresponding amino acid changes, which could be used as a specific candidate site for this gene. At the same time, there were differences in NFKB1 gene between foreign chicken breeds and local chicken breeds, egg type and meat type chicken breeds, which provided reference for further study of the differences among different chicken breeds.
【作者单位】： 扬州大学动物科学与技术学院;中国农业科学院家禽研究所;
【基金】：“十二五”国家科技支撑计划项目(2015BAD03B03) 江苏省科技支撑计划项目(BE2013392)
【分类号】：S831.2
本文编号：2500502
[Abstract]:The SNPs polymorphism of NFKB1 gene was detected by target capture and sequencing technique in 27 chicken breeds, and the genetic effect of NFKB1 gene was analyzed, and the relationship between NFKB1 gene polymorphism and different chicken breeds was discussed by constructing phylogenetic tree by maximum reduction method. The results showed that there were 233mutation sites in NFKB1 gene of 27 chicken breeds, of which 6 mutation sites existed in exons, showing rich gene polymorphism, and the SNPs loci in exon14 existed specifically in recessed white feather chickens and AA chickens, and caused corresponding amino acid changes, which could be used as a specific candidate site for this gene. At the same time, there were differences in NFKB1 gene between foreign chicken breeds and local chicken breeds, egg type and meat type chicken breeds, which provided reference for further study of the differences among different chicken breeds.
【作者单位】： 扬州大学动物科学与技术学院;中国农业科学院家禽研究所;
【基金】：“十二五”国家科技支撑计划项目(2015BAD03B03) 江苏省科技支撑计划项目(BE2013392)
【分类号】：S831.2
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，本文编号：2500502
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